Table 3 Associations with high Gal3BP for all, women and men
Variables | High galectin-3BP (≥3.3 mg/l, ≥80th percentile) | |||||||
|---|---|---|---|---|---|---|---|---|
All patients | Women | Men | ||||||
COR | p value | AOR | p valuea | AOR | p valueb | AOR | p valuec | |
Sex (women) | 2.7 (1.5–4.9) | 0.001 | 3.0 (1.5–5.9) | 0.001 | – | – | – | – |
Age | 0.99 (0.97–1.02) | 0.43 | 1.02 (0.99–1.05) | 0.22 | 0.98 (0.94–1.02) | 0.27 | 1.03 (0.98–1.08) | 0.30 |
Diabetes duration | 0.98 (0.95–1.00) | 0.076 | 0.98 (0.95–1.00) | 0.11 | – | – | 0.96 (0.92–1.01) | 0.14 |
sCD163 (mg/l) | 5.4 (1.6–18.0) | 0.005 | 6.6 (1.9–23.2) | 0.003 | 4.6 (0.8–26.9) | 0.093 | 11.2 (2.0–64.5)) | 0.007 |
Galectin-3 (μg/l) | 1.04 (0.99–1.10) | 0.14 | – | – | – | – | – | – |
HbA1c mmol/mol | 1.03 (1.01–1.05) | 0.008 | 1.02 (1.00–1.04) | 0.09 | 1.03 (1.00–1.06) | 0.039 | – | – |
TC (mmol/l) | 1.4 (1.0–1.8) | 0.022 | 1.6 (1.1–2.2) | 0.007 | – | – | 2.3 (1.3–3.9) | 0.003 |
Triglycerides (mmol/l) | 1.5 (1.1–2.1) | 0.014 | 0.9 (0.5–1.5) | 0.58 | – | – | 0.7 (0.4–1.5) | 0.41 |
LDL-cholesterol (mmol/l) | 1.5 (1.1–2.2) | 0.017 | 0.6 (0.1–3.5) | 0.53 | 1.1 (0.6–1.8) | 0.76 | 0.4 (0.03–6.6) | 0.56 |
HDL-cholesterol (mmol/l) | 0.45 (0.2–1.0) | 0.059 | 0.2 (0.1–0.7) | 0.010 | – | – | 0.2 (0.02–0.9) | 0.040 |
Creatinine | 0.99 (0.97–1.01) | 0.16 | – | – | – | – | – | – |
Abdominal obesity | 1.1 (0.5–2.4) | 0.77 | – | – | – | – | – | – |
General obesity | 3.4 (1.6–7.2) | 0.002 | 1.6 (0.7–4.0) | 0.29 | – | – | 7.9 (1.9–32.6) | 0.004 |
SBP | 0.99 (0.96–1.01) | 0.26 | – | – | – | – | – | – |
DBP | 1.00 (0.96–1.04) | 0.83 | – | – | – | – | – | – |
Smoking | 1.2 (0.5–3.1) | 0.74 | – | – | – | – | – | – |
Physical inactivity | 2.3 (1.0–5.2) | 0.053 | 1.8 (0.7–4.8) | 0.22 | – | – | – | – |
Depression | 0.6 (0.2–1.3) | 0.19 | – | – | – | – | – | – |
CV complications | 2.7 (0.7–9.8) | 0.14 | – | – | 4.0 (0.3–47.3) | 0.26 | – | – |
Diabetes retinopathy | 1.0 (0.5–2.0) | 0.93 | – | – | – | – | – | – |
Foot complications | 1.3 (0.6–2.7) | 0.54 | – | – | – | – | – | – |
AD | 1.8 (0.7–4.5) | 0.24 | – | – | 2.6 (0.7–9.4) | 0.15 | – | – |
AHD | 0.9 (0.5–1.7) | 0.79 | – | – | – | – | – | – |
LLD | 1.2 (0.7–2.2) | 0.47 | – | – | – | – | – | – |