Variables
|
High galectin-3BP (≥3.3 mg/l, ≥80th percentile)
|
---|
All patients
|
Women
|
Men
|
---|
COR
|
p value
|
AOR
|
p valuea
|
AOR
|
p valueb
|
AOR
|
p valuec
|
---|
Sex (women)
|
2.7 (1.5–4.9)
|
0.001
|
3.0 (1.5–5.9)
|
0.001
|
–
|
–
|
–
|
–
|
Age
|
0.99 (0.97–1.02)
|
0.43
|
1.02 (0.99–1.05)
|
0.22
|
0.98 (0.94–1.02)
|
0.27
|
1.03 (0.98–1.08)
|
0.30
|
Diabetes duration
|
0.98 (0.95–1.00)
|
0.076
|
0.98 (0.95–1.00)
|
0.11
|
–
|
–
|
0.96 (0.92–1.01)
|
0.14
|
sCD163 (mg/l)
|
5.4 (1.6–18.0)
|
0.005
|
6.6 (1.9–23.2)
|
0.003
|
4.6 (0.8–26.9)
|
0.093
|
11.2 (2.0–64.5))
|
0.007
|
Galectin-3 (μg/l)
|
1.04 (0.99–1.10)
|
0.14
|
–
|
–
|
–
|
–
|
–
|
–
|
HbA1c mmol/mol
|
1.03 (1.01–1.05)
|
0.008
|
1.02 (1.00–1.04)
|
0.09
|
1.03 (1.00–1.06)
|
0.039
|
–
|
–
|
TC (mmol/l)
|
1.4 (1.0–1.8)
|
0.022
|
1.6 (1.1–2.2)
|
0.007
|
–
|
–
|
2.3 (1.3–3.9)
|
0.003
|
Triglycerides (mmol/l)
|
1.5 (1.1–2.1)
|
0.014
|
0.9 (0.5–1.5)
|
0.58
|
–
|
–
|
0.7 (0.4–1.5)
|
0.41
|
LDL-cholesterol (mmol/l)
|
1.5 (1.1–2.2)
|
0.017
|
0.6 (0.1–3.5)
|
0.53
|
1.1 (0.6–1.8)
|
0.76
|
0.4 (0.03–6.6)
|
0.56
|
HDL-cholesterol (mmol/l)
|
0.45 (0.2–1.0)
|
0.059
|
0.2 (0.1–0.7)
|
0.010
|
–
|
–
|
0.2 (0.02–0.9)
|
0.040
|
Creatinine
|
0.99 (0.97–1.01)
|
0.16
|
–
|
–
|
–
|
–
|
–
|
–
|
Abdominal obesity
|
1.1 (0.5–2.4)
|
0.77
|
–
|
–
|
–
|
–
|
–
|
–
|
General obesity
|
3.4 (1.6–7.2)
|
0.002
|
1.6 (0.7–4.0)
|
0.29
|
–
|
–
|
7.9 (1.9–32.6)
|
0.004
|
SBP
|
0.99 (0.96–1.01)
|
0.26
|
–
|
–
|
–
|
–
|
–
|
–
|
DBP
|
1.00 (0.96–1.04)
|
0.83
|
–
|
–
|
–
|
–
|
–
|
–
|
Smoking
|
1.2 (0.5–3.1)
|
0.74
|
–
|
–
|
–
|
–
|
–
|
–
|
Physical inactivity
|
2.3 (1.0–5.2)
|
0.053
|
1.8 (0.7–4.8)
|
0.22
|
–
|
–
|
–
|
–
|
Depression
|
0.6 (0.2–1.3)
|
0.19
|
–
|
–
|
–
|
–
|
–
|
–
|
CV complications
|
2.7 (0.7–9.8)
|
0.14
|
–
|
–
|
4.0 (0.3–47.3)
|
0.26
|
–
|
–
|
Diabetes retinopathy
|
1.0 (0.5–2.0)
|
0.93
|
–
|
–
|
–
|
–
|
–
|
–
|
Foot complications
|
1.3 (0.6–2.7)
|
0.54
|
–
|
–
|
–
|
–
|
–
|
–
|
AD
|
1.8 (0.7–4.5)
|
0.24
|
–
|
–
|
2.6 (0.7–9.4)
|
0.15
|
–
|
–
|
AHD
|
0.9 (0.5–1.7)
|
0.79
|
–
|
–
|
–
|
–
|
–
|
–
|
LLD
|
1.2 (0.7–2.2)
|
0.47
|
–
|
–
|
–
|
–
|
–
|
–
|
- a, b, c Logistic regression analyses (Backward: Wald): variables with p values ≤0.10 for the CORs and age were included in the analyses; N = a 267/b 123/c 160; Nagelkerke R2: a 0.206/ b 0.089/c 0.298; Hosmer-Lemeshow test: a 0.991/b 0.142/c 0.821