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Table 3 Associations with high Gal3BP for all, women and men

From: Female sex, high soluble CD163, and low HDL-cholesterol were associated with high galectin-3 binding protein in type 1 diabetes

VariablesHigh galectin-3BP (≥3.3 mg/l, ≥80th percentile)
All patientsWomenMen
CORp valueAORp valueaAORp valuebAORp valuec
Sex (women)2.7 (1.5–4.9)0.0013.0 (1.5–5.9)0.001
Age0.99 (0.97–1.02)0.431.02 (0.99–1.05)0.220.98 (0.94–1.02)0.271.03 (0.98–1.08)0.30
Diabetes duration0.98 (0.95–1.00)0.0760.98 (0.95–1.00)0.110.96 (0.92–1.01)0.14
sCD163 (mg/l)5.4 (1.6–18.0)0.0056.6 (1.9–23.2)0.0034.6 (0.8–26.9)0.09311.2 (2.0–64.5))0.007
Galectin-3 (μg/l)1.04 (0.99–1.10)0.14
HbA1c mmol/mol1.03 (1.01–1.05)0.0081.02 (1.00–1.04)0.091.03 (1.00–1.06)0.039
TC (mmol/l)1.4 (1.0–1.8)0.0221.6 (1.1–2.2)0.0072.3 (1.3–3.9)0.003
Triglycerides (mmol/l)1.5 (1.1–2.1)0.0140.9 (0.5–1.5)0.580.7 (0.4–1.5)0.41
LDL-cholesterol (mmol/l)1.5 (1.1–2.2)0.0170.6 (0.1–3.5)0.531.1 (0.6–1.8)0.760.4 (0.03–6.6)0.56
HDL-cholesterol (mmol/l)0.45 (0.2–1.0)0.0590.2 (0.1–0.7)0.0100.2 (0.02–0.9)0.040
Creatinine0.99 (0.97–1.01)0.16
Abdominal obesity1.1 (0.5–2.4)0.77
General obesity3.4 (1.6–7.2)0.0021.6 (0.7–4.0)0.297.9 (1.9–32.6)0.004
SBP0.99 (0.96–1.01)0.26
DBP1.00 (0.96–1.04)0.83
Smoking1.2 (0.5–3.1)0.74
Physical inactivity2.3 (1.0–5.2)0.0531.8 (0.7–4.8)0.22
Depression0.6 (0.2–1.3)0.19
CV complications2.7 (0.7–9.8)0.144.0 (0.3–47.3)0.26
Diabetes retinopathy1.0 (0.5–2.0)0.93
Foot complications1.3 (0.6–2.7)0.54
AD1.8 (0.7–4.5)0.242.6 (0.7–9.4)0.15
AHD0.9 (0.5–1.7)0.79
LLD1.2 (0.7–2.2)0.47
  1. a, b, c Logistic regression analyses (Backward: Wald): variables with p values ≤0.10 for the CORs and age were included in the analyses; N = a 267/b 123/c 160; Nagelkerke R2: a 0.206/ b 0.089/c 0.298; Hosmer-Lemeshow test: a 0.991/b 0.142/c 0.821