Skip to main content

Table 2 Female-biased expression of transcription and epigenetic factors

From: The developmental origins of sex-biased expression in cardiac development

Transcription factors and epigenetic remodelling enzymes

ES

CP

8.5

9.5

10.5

p1

Adult

Chr

Name

Hmgb3

XX

      

X

High mobility group box 3

Dmrtb1

XX

      

4

DMRT-like family B with proline-rich C-terminal, 1

Hoxb9

XX

      

11

Homeobox B9

Hoxc8

XX

      

15

Homeobox C8

Klf8

XX

      

X

Kruppel-like factor 8

Mitf

XX

      

6

Melanogenesis associated transcription factor

Prdm14

XX

      

1

PR domain containing 14

Rhox1

XX

      

X

Reproductive homeobox 1

Sohlh2

XX

      

3

Spermatogenesis and oogenesis specific basic helix-loop-helix 2

Spic

XX

      

13

Serine (or cysteine) peptidase inhibitor, clade B, member 6c

Tbx15

XX

      

3

T-box 15

Zeb1

XX

      

18

Zinc finger E-box binding homeobox 1

Zfp182

XX

      

X

Zinc finger protein 182

Zfp275

XX

      

X

Zinc finger protein 275

Zfp449

XX

      

X

Zinc finger protein 449

Zfp59

XX

      

7

Zinc finger protein 59

Zxdb

XX

      

X

Zinc finger, X-linked, duplicated B

Mecp2

XX

      

X

Methyl CpG binding protein 2

Nkap

XX

      

X

NFKB activating protein

Ogt

XX

      

X

O-linked N-acetylglucosamine (GlcNAc) transferase

Top2b

XX

      

14

Topoisomerase (DNA) II beta

Trim16

XX

      

11

Tripartite motif-containing 16

Zmym3

XX

      

X

Zinc finger, MYM-type 3

Apobec2

XX

      

17

Apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2

Baz2b

XX

      

2

Bromodomain adjacent to zinc finger domain, 2B

Prrx1

XX

XX

     

1

Paired related homeobox 1

Kdm6a

XX

    

XX

XX

X

Lysine (K)-specific demethylase 6A

Lbh

XX

     

XX

17

Limb-bud and heart

Meis2

XX

     

XY

2

Meis homeobox 2

Zfp9

XX

     

XY

6

Zinc finger protein 9

Aff2

XX

    

XX

nb

X

AF4/FMR2 family, member 2

Atrx

XX

    

XY

nb

X

ATRX, chromatin remodeler

Arid1b

nb

  

XX

XX

 

nb

17

AT rich interactive domain 1B (SWI-like)

Bhlhe40

nb

  

XX

  

XX

6

Basic helix-loop-helix family, member e40

Zfp51

nb

  

XX

  

XX

17

Zinc finger protein 51

Klf15

nb

     

XX

6

Kruppel-like factor 15

Mafk

nb

    

XX

XX

5

v-Maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)

Aff3

nb

XX

 

XX

 

XX

XY

 

AF4/FMR2 Family Member 3

Heyl

     

XX

 

4

Hairy/enhancer-of-split related with YRPW motif-like

Hopx

     

XX

 

5

HOP homeobox

Dlx1

     

XX

 

2

Distal-less homeobox 1

Rsl1

     

XX

 

13

Regulator of sex limited protein 1

Zbtb45

     

XX

 

7

Zinc finger and BTB domain containing 45

Zfp282

     

XX

 

6

Zinc finger protein 282

Zfp472

     

XX

 

17

Zinc finger protein 472

Zfp498

     

XX

 

5

Zinc finger and SCAN domain containing 25

Zfp758

     

XX

 

17

Zinc finger protein 758

Zkscan14

     

XX

 

5

Zinc finger with KRAB and SCAN domains 14

Zkscan6

     

XX

 

11

Zinc finger with KRAB and SCAN domains 6

Nat10

     

XX

 

2

N-acetyltransferase 10

Senp3

     

XX

 

11

SUMO/sentrin specific peptidase 3

Setmar

     

XX

 

6

SET domain without mariner transposase fusion

Sirt7

     

XX

 

11

sirtuin 7

Suv39h2

     

XX

 

2

suppressor of variegation 3-9 2

Bard1

     

XX

 

1

BRCA1 associated RING domain 1

Cbx2

     

XX

 

11

Chromobox 2

Cbx7

     

XX

 

15

Chromobox 7

Rcc1

     

XX

 

4

Regulator of chromosome condensation 1

Nkx2-5

     

XX

XX

17

NK2 homeobox 5

Irf4

      

XX

13

Interferon regulatory factor 4

Cecr2

      

XX

6

CECR2, histone acetyl-lysine reader

  1. ES embryonic stem cells; CP cardiac precursors; 8.5, 9.5, 10.5 days post coitum (dpc) embryonic hearts (single cell); p1 neonatal hearts; Chr chromosome; empty cells expression not detected; nb expressed but not biased