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Table 2 Regression analysis of insulin tolerance testing results in Figs. 2 and 3

From: Sex differences in metabolic effects of angiotensin-(1-7) treatment in obese mice

  Estimate SE T-statistic P value
Fasting Glucose
 Drug (=Ang-(1-7)) 19.421 11.091 1.751 0.084
 Diet (=HFD) 20.288 10.511 1.930 0.058
 Sex (=female) − 15.141 11.645 − 1.300 0.198
Fasting Insulin
 Drug (=Ang-(1-7)) 0.291 0.530 0.549 0.585
 Diet (=HFD) 2.722 0.502 5.422 0.001
 Sex (=female) − 0.707 0.556 − 1.271 0.208
 Diet:Sex − 2.120 0.628 − 3.375 0.001
AUC Glucose
 Drug (=Ang-(1-7)) − 43.09 1045.98 − 0.041 0.967
 Diet (=HFD) 5284.48 991.32 5.331 0.001
 Sex (=female) − 872.61 1098.21 − 0.795 0.430
 Drug:Diet − 3998.21 1224.93 − 3.264 0.002
  1. Data were analyzed by multiple regressions with the adjusted P values obtained based on Wald tests. Results are shown for main effects of drug, diet, and sex and for interactions when reaching statistical significance (P < 0.05). SE standard error, AUC area under the curve