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Table 4 Number of drugs taken by male and female MS patients in different age groups

From: Polypharmacy in patients with multiple sclerosis: a gender-specific analysis

  Age (years) ≤ 29 30–39 40–49 50–59 ≥ 60
N 23 64 64 96 59
Number of PwP (%) Female 4 (20.0) 16 (34.8) 23 (54.8) 40 (60.6) 39 (88.6)
Male 1 (33.3) 8 (44.4) 10 (45.5) 20 (66.7) 12 (80.0)
  p valueFi 0.539 0.569 0.600 0.653 0.407
Number of drugsa Female 3.1 (1.4) 4.1 (2.1) 5.1 (3.1) 6.3 (3.7) 9.0 (4.1)
Male 4.0 (2.0) 4.6 (2.7) 4.7 (3.3) 5.3 (2.8) 7.3 (3.5)
  p valuet 0.316 0.501 0.638 0.178 0.152
Mean difference in the number of drugs* − 0.9 − 0.5 0.4 1.0 1.7
  1. N number of patients, PwP patients with polypharmacy
  2. *Differences in the average number of medications taken by female and male MS patients: The differences correlated with the age grouping (Pearson coefficient = 0.995 and p < 0.001). Women thus showed a significantly stronger age-related increase in the number of drugs used compared to men
  3. aMean value (standard deviation)
  4. FiFisher’s exact test
  5. tTwo-sample two-tailed Student’s t test