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Table 2 Renal lobar artery reactivity

From: Chronic low alcohol intake during pregnancy programs sex-specific cardiovascular deficits in rats

 

Females

Males

Two-way ANOVA

Control

EtOH-exposed

Control

EtOH-exposed

P trt

P sex

P trt*sex

HiK

 Contraction (mN mm−1)

10.9 ± 0.4

11.4 ± 0.7

11.4 ± 1.1

10.8 ± 0.8

NS

NS

NS

PE

 pEC50

7.03 ± 0.15

6.96 ± 0.12

7.12 ± 0.04

7.25 ± 0.06

NS

NS

NS

 Max. contraction (% HiK)

113 ± 2

117 ± 2

111 ± 3

116 ± 4

NS

NS

NS

AngII

 pEC50

8.17 ± 0.26

8.16 ± 0.09

8.47 ± 0.15

8.44 ± 0.17

NS

NS

NS

 Max. contraction (% HiK)

21 ± 6

26 ± 10

33 ± 13

34 ± 13

NS

NS

NS

SNP

 pEC50

8.07 ± 0.10

8.05 ± 0.07

7.95 ± 0.10

7.89 ± 0.09

NS

NS

NS

 Rmax (%)

95 ± 2

91 ± 5

96 ± 3

97 ± 1

NS

NS

NS

ACh

 pEC50

6.85 ± 0.23

6.99 ± 0.15

6.79 ± 0.09

6.97 ± 0.18

NS

NS

NS

 Rmax (%)

94 ± 3

97 ± 1

89 ± 6

92 ± 6

NS

NS

NS

ACh + L-NAME + INDO

 pEC50

7.18 ± 0.21

6.98 ± 0.24

7.27 ± 0.16

7.26 ± 0.32

NS

NS

NS

 Rmax (%)

34 ± 7

48 ± 10

19 ± 3

21 ± 5

NS

P = 0.04

NS

  1. Values are mean ± SEM (n = 6–7 per group). The effect of prenatal treatment (trt), sex or their interaction (trt*sex) was evaluated by two-way ANOVA. Max. maximal