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Table 2 Renal lobar artery reactivity

From: Chronic low alcohol intake during pregnancy programs sex-specific cardiovascular deficits in rats

  Females Males Two-way ANOVA
Control EtOH-exposed Control EtOH-exposed P trt P sex P trt*sex
HiK
 Contraction (mN mm−1) 10.9 ± 0.4 11.4 ± 0.7 11.4 ± 1.1 10.8 ± 0.8 NS NS NS
PE
 pEC50 7.03 ± 0.15 6.96 ± 0.12 7.12 ± 0.04 7.25 ± 0.06 NS NS NS
 Max. contraction (% HiK) 113 ± 2 117 ± 2 111 ± 3 116 ± 4 NS NS NS
AngII
 pEC50 8.17 ± 0.26 8.16 ± 0.09 8.47 ± 0.15 8.44 ± 0.17 NS NS NS
 Max. contraction (% HiK) 21 ± 6 26 ± 10 33 ± 13 34 ± 13 NS NS NS
SNP
 pEC50 8.07 ± 0.10 8.05 ± 0.07 7.95 ± 0.10 7.89 ± 0.09 NS NS NS
Rmax (%) 95 ± 2 91 ± 5 96 ± 3 97 ± 1 NS NS NS
ACh
 pEC50 6.85 ± 0.23 6.99 ± 0.15 6.79 ± 0.09 6.97 ± 0.18 NS NS NS
Rmax (%) 94 ± 3 97 ± 1 89 ± 6 92 ± 6 NS NS NS
ACh + L-NAME + INDO
 pEC50 7.18 ± 0.21 6.98 ± 0.24 7.27 ± 0.16 7.26 ± 0.32 NS NS NS
Rmax (%) 34 ± 7 48 ± 10 19 ± 3 21 ± 5 NS P = 0.04 NS
  1. Values are mean ± SEM (n = 6–7 per group). The effect of prenatal treatment (trt), sex or their interaction (trt*sex) was evaluated by two-way ANOVA. Max. maximal