Table 4 Rates of change in postoperative cognitive test scores in men vs. women stratified by APOE4 status—APOE4− carriers
From: Sex and genetic differences in postoperative cognitive dysfunction: a longitudinal cohort analysis
Men APOE4− non-surgical (slope) n = 177 | Women APOE4− non-surgical (slope) n = 348 | Men APOE4− surgical (slope) n = 69 | Women APOE4− surgical (slope) n = 123 | Surgical-sex interaction on rate of change—Non-Carriers (p value) | ||
|---|---|---|---|---|---|---|
Global cognitive function tests | MMSE | − 0.01485 | − 0.01571 | − 0.01948 | − 0.02411 | 0.15 |
CDR-SB | 0.2749 | 0.2654169 | 0.3305 | 0.3888 | 0.02 | |
Memory-based tests | Logical Memory Delayed Recall | − 0.05689 | − 0.05369 | − 0.1959 | − 0.2873 | 0.19 |
CERAD Delayed Word List | − 0.03427 | − 0.04447 | − 0.04921 | − 0.05608 | 0.64 | |
Attention-based tests | Digit Symbol | − 0.9422 | − 0.9187 | − 1.297 | − 1.232 | 0.78 |
SDMT | − 0.03789 | − 0.02705 | − 0.02942 | − 0.03062 | 0.21 | |
Executive function tests | Trails Making Test B | 7.005 | 3.892 | 3.388 | 6.532 | 0.96 |
Animal Category Fluency | − 0.4282 | − 0.3635 | − 0.5056 | − 0.5563 | 0.15 | |