Group
|
Body weight in grams (SEM)
|
Adrenal weight in grams (SEM)
|
---|
Baseline
|
Post-test
|
---|
Sham
|
Ctrl
|
199.4 (2.7)
|
213.0* (2.9)
|
0.34 (0.02)
|
n = 16/gp
|
SPS
|
199.4 (3.8)
|
209.4* (4.1)
|
0.37 (0.03)
|
GDX
|
Ctrl
|
215.7+ (4.3)
|
243.5*+ (4.5)
|
0.31 (0.01)
|
n = 15/gp
|
SPS
|
214.2+ (2.6)
|
234.5*+ (3.1)
|
0.30 (0.04)
|
GDX + T
|
Ctrl
|
227.0+ (4.9)
|
255.7*+ (5.9)
|
0.23 (0.03)
|
n = 11/gp
|
SPS
|
223.9+ (4.8)
|
246.2*+ (6.4)
|
0.27 (0.02)
|
- Rat body weights were collected before undergoing SPS or control conditions (baseline) and before the dexamethasone suppression test (post-test). Adrenal weights were collected after sacrifice. Neither SPS nor testosterone (T) affected body or adrenal weight in females, and all rats gained weight over the course of the experiment (*, vs baseline). As expected, gonadectomy (GDX) increased female body weight (+, vs sham). Data was presented as mean±SEM. Significance set at P < .05 (indicated by asterisk) for planned pairwise comparisons (Bonferroni). Refer to Additional file 5 for full statistical results