Skip to main content

Table 3 Age specific hazard ratios (HR) for epilepsy in OS twins compared with SS twins

From: Risk of epilepsy in opposite-sex and same-sex twins: a twin cohort study

Age group and exposure status Female Males
Population Epilepsy cases IRa Crude HR Adjusted HR [95% CI]b Population Epilepsy cases IRa Crude HR Adjusted HR [95% CI]b
<1 year  
 SS 19,186 47 26.66 Ref Ref 20,207 63 33.99 Ref Ref
 OS 11,078 19 18.65 0.70 0.74[0.42-1.30] 11,080 34 33.40 0.98 0.98[0.63-1.51]
1-9 years
 SS 19,039 130 9.04 Ref Ref 19,990 176 11.60 Ref Ref
 OS 11,004 86 10.55 1.16 1.17[0.89-1.55] 10,992 87 10.69 0.92 0.95[0.73-1.23]
10-18 years
 SS 12,379 73 8.81 Ref Ref 13,150 70 8.01 Ref Ref
 OS 6,722 35 8.38 0.95 0.95[0.63-1.44] 6,713 34 8.16 1.01 0.98[0.65-1.48]
19-35 years
 SS 6,282 32 7.06 Ref Ref 6,533 26 5.19 Ref Ref
 OS 2,805 12 6.05 0.86 0.87[0.45-1.69] 2,789 7 3.58 0.69 0.72[0.31-1.66]
  1. aIncidence rate (/10,000 person-years)
  2. bHazard ratios, adjusted for maternal age at time of birth (<25, 25-29, 30-34, 35-39, 40+ years), paternal age at time of birth (<30, 30-39, 40+ years, missing), maternal and paternal highest completed education (primary and lower secondary, upper and post-secondary, tertiary, and missing), and calendar year (1977-1984, 1985-1994, 1995-1999, 2000-2004, 2005-2009)