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Table 2 Hazard ratios (HR) for epilepsy in OS twins compared with SS twins in females and males

From: Risk of epilepsy in opposite-sex and same-sex twins: a twin cohort study

Exposure status Both twins of the SS twin pair were included in the reference One twin of the SS twin pair was randomly selected as the reference
Sample 1 Sample 2
Population Epilepsy cases IRa Crude HR Adjusted HR [95% CI]b Adjusted HR [95% CI]b Adjusted HR [95% CI]b
The SS female twins 19,186 282 9.74 Ref Ref Ref Ref
The OS female twins 11,078 152 9.91 1.00 1.01[0.83-1.24] 1.03[0.81-1.30] 1.00[0.79-1.25]
The SS male twins 20,207 335 10.9 Ref Ref Ref Ref
The OS male twins 11,080 162 10.6 0.93 0.94[0.78-1.14] 1.00[0.80-1.24] 0.89[0.72-1.11]
  1. aIncidence rate (/10,000 person-years)
  2. bHazard ratios are adjusted for maternal age at time of birth (<25, 25-29, 30-34, 35-39, 40+ years), paternal age at time of birth (<30, 30-39, 40+ years, missing), maternal and paternal highest completed education (primary and lower secondary, upper and post-secondary, tertiary, and missing), and calendar year (1977-1984, 1985-1994, 1995-1999, 2000-2004, 2005-2009)