Fig. 6

Protective effect of SAHA on NIHL—both sexes combined. Threshold shifts were compared between SAHA- and vehicle-treated animals at 24 h (a) and 15 days (b) post-noise exposure. The dots indicate individual ear threshold shifts; the upper and lower whiskers indicate the maximum and minimum shifts, respectively. a CTS values suggested a protective effect of SAHA at 16 kHz (*p = 0.007). b PTS values suggested a protective effect of SAHA at 16 kHz (*p = 0.0095) and 24 kHz (**p = 0.0024)