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Fig. 4 | Biology of Sex Differences

Fig. 4

From: Effects of gut-derived endotoxin on anxiety-like and repetitive behaviors in male and female mice

Fig. 4

Effects of oral gavage of LPS on male and female WT mice. Experiment 2: effects of intraperitoneal injection of TLR4 antagonists and oral gavage of LPS on open field test behavioral outcomes in male and female WT mice. Data presented as sex by gavage treatment. LPS significantly a decreased zone entries and b increased the number of rears in males and females relative to saline-treated subjects. Furthermore, LPS significantly decreased the number of c time spent in stereotypic circling, d stereotypic counts, and e jump counts relative to saline-treated subjects. In addition, females had a higher jump count than males. Error bars are 95% confidence intervals. *p < 0.05; (*) significant main effect of sex, p < 0.05

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