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Table 6 Genes significantly upregulated in males (downregulated in females)

From: Sex differences in the late first trimester human placenta transcriptome

Gene symbol Chr Description Fold-change (M/F) FDRa FPKM in F FPKM in M
RPS4Y1 Y Ribosomal protein S4, Y-linked 1 203.657 0 0.01 61.83
DDX3Y Y DEAD-box helicase 3, Y-linked 167.730 0 0.01 21.83
KDM5D Y Lysine demethylase 5D 160.898 0 0.00 6.73
USP9Y Y Ubiquitin specific peptidase 9, Y-linked 110.661 0 0.00 6.27
ZFY Y Zinc finger protein, Y-linked 83.865 0 0.00 5.66
UTY Y Ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 83.286 0 0.00 7.99
TTTY15 Y Testis-specific transcript, Y-linked 15 (non-protein coding) 78.249 0 0.00 4.42
EIF1AY Y Eukaryotic translation initiation factor 1A, Y-linked 62.683 0 0.01 6.11
LINC00278 Y Long intergenic non-protein coding RNA 278 15.671 1.51E-127 0.02 5.44
TTTY14 Y Testis-specific transcript, Y-linked 14 (non-protein coding) 13.548 4.73E-108 0.01 1.69
ANOS2P Y Anosmin 2, pseudogene 12.295 2.38E-102 0.01 1.28
PCDH11Y Y Protocadherin 11 Y-linked 12.042 7.38E-132 0.08 2.30
TXLNGY Y Taxilin gamma pseudogene, Y-linked 9.714 1.44E-75 0.00 1.37
ZFY-AS1 Y ZFY antisense RNA 1 8.056 7.64E-66 0.02 1.97
PSMA6P1 Y Proteasome subunit alpha 6 pseudogene 1 3.482 6.21E-27 0.40 2.02
ARMCX6 X Armadillo repeat containing, X-linked 6 1.795 7.62E-06 1.78 3.95
MTRNR2L8 11 MT-RNR2-like 8 1.613 0.0201 2.90 4.88
ARMCX3 X Armadillo repeat containing, X-linked 3 1.609 0.000255 6.70 11.93
HMGCS2 1 3-hydroxy-3-methylglutaryl-CoA synthase 2 1.603 0.035 1.99 4.27
FRG1JP 9 FSHD region gene 1 family member J, pseudogene 1.507 0.0209 1.36 2.27
HSPB1 7 Heat shock protein family B (small) member 1 1.486 0.0482 41.94 65.09
TLE2 19 Transducin-like enhancer of split 2 1.409 0.0495 2.61 3.67
ARHGEF9 X Cdc42 guanine nucleotide exchange factor 9 1.344 0.0416 1.28 1.75
  1. Sorted by fold-change. F = females. M = males
  2. aBenjamini-Hochberg false discovery rate
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