Skip to main content

Table 2 I/R-induced changes in gene expression in female forepaw muscles and C7/C8/T1 DRGs relative to naïves

From: Sex differences in primary muscle afferent sensitization following ischemia and reperfusion injury

Gene DRG expression Gene Muscle expression
GFRα3 4.5 ± 24% Artemin − 38.1 ± 43%
IL6R − 20.8 ± 46% GDNF 42.5 ± 26%
P2X4 108.3 ± 15% * IL-1β − 7.6 ± 62%
P2Y1 − 6.3 ± 22% IL-6 − 44.3 ± 53%
TNFαR − 20.7 ± 45% MCP-1 53.4 ± 75%
   NGF − 14.6 ± 15%
   NT-3 − 10.5 ± 25%
   TNFα − 2.5 ± 29%
  1. Values indicate percentage change relative to sex- and age-matched naïve controls ± error of the difference in means (n = 6–11 per condition). *P < .05 vs. naïve obtained via Mann-Whitney Rank-Sum tests for each gene on raw sample ∆Cts, followed by the false discovery rate multiple comparisons correction within each tissue type
\