Fig. 5
From: Sex-specific phenotypes of hyperthyroidism and hypothyroidism in aged mice
Rotarod performance in all groups in both ages and sexes under control, T4 or MMI/ClO4−/LoI treatment. Time spend on the rotating cylinder was determined in adult (a-c) and old (d-f) male and female mice. For each mouse, a training period was implemented in euthyroid state and was compared to the performance under hyper-, hypo- or again euthyroid state. Pronounced sex difference in euthyroid mice was diminished by TH excess or deprivation. Data are presented as mean ± SD, n = 7–11 animals/sex/treatment, unpaired two-tailed Student’s t test, *p < 0.05, **p < 0.01, ***p < 0.001