Fig. 2
From: Sex influences eQTL effects of SLE and Sjögren’s syndrome-associated genetic polymorphisms
eQTL effects of disease polymorphisms differ between males (left column, blue boxes) and females (right column, red boxes). a Genotypic effects of the proxy SNP rs4637409 (r 2 = 1) for the SLE-associated rs10516487 (BANK1 locus) on expression of SLC39A8 (ILMN_1695316 probe) in males (p = 0.041) and females (p = 0.052). b Genotypic effects of the proxy SNP rs10036748 (r 2 = 1) for the SLE-associated rs7708392 (TNIP1 locus) on expression of CD74 (ILMN_2379644 probe) in males (p = 0.065) and females (p = 0.048). c Genotypic effects of the SLE-associated rs6445975 (PXK locus) on expression of PXK (ILMN_1815063 probe) in males (p = 0.60) and females (p = 0.0029). The rightmost genotype group in each graph denotes the homozygous group of the disease risk allele and is marked by an asterisk. Statistics in boxes represent the SNP * Sex interaction term analysis