Table 6 Effects of age (breakpoint >55 years) on ACE, ACE2, NEP, APN, and APA serum activities in women and men
From: Sex differences in the aging pattern of renin–angiotensin system serum peptidases
<55 years | ≥ 55 years | Mann–Whitney U | |||||||
|---|---|---|---|---|---|---|---|---|---|
Median | IQR | N | Median | IQR | N | Z | P value | ||
WOMEN | ACE | 820.3 | 249.77 | 28 | 815.9 | 272.13 | 30 | −0.731 | 0.465 |
ACE2 | 61.71 | 16.69 | 28 | 71.11 | 16.22 | 30 | −2.169 | 0.030 | |
NEP | 15474 | 1187.55 | 28 | 15703 | 1812.15 | 30 | −0.965 | 0.335 | |
APN | 9931 | 5046.74 | 28 | 10238 | 6688.67 | 30 | −0.747 | 0.455 | |
APA | 4304 | 1225.79 | 28 | 4361 | 1240.15 | 30 | −0.327 | 0.744 | |
MEN | ACE | 841.4 | 281.02 | 31 | 744.4 | 201.43 | 29 | −1.960 | 0.049 |
ACE2 | 59.75 | 23.57 | 31 | 70.05 | 30.92 | 29 | −1.007 | 0.313 | |
NEP | 16203 | 2030.32 | 31 | 15344 | 1668.93 | 29 | −1.013 | 0.311 | |
APN | 11517 | 6916.75 | 31 | 9973 | 4001.23 | 29 | −1.620 | 0.105 | |
APA | 4281 | 1633.4 | 31 | 3820 | 623.97 | 29 | −1.856 | 0.063 | |