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Table 4 Renin–angiotensin system-regulating enzyme activities and sex differences

From: Sex differences in the aging pattern of renin–angiotensin system serum peptidases

 

TOTAL

WOMEN

MEN

Mann–Whitney U

Median

IQR

N

Median

IQR

N

Median

IQR

N

Z

P value

ACE

783.3

253.31

118

820.3

253.32

58

771.3

254.27

60

−1.281

0.2

ACE2

64.33

21.59

118

64.66

18.49

58

63.12

27.14

60

−0.350

0.726

NEP

15702

1724.59

118

15594

1272.12

58

15846

1974.44

60

−1.066

0.286

APN

10260

5417.84

118

10238

599.2

58

10436

4937.59

60

−0.711

0.477

APA

4143

1296.75

118

4345

1225.79

58

3946

991.35

60

−2.153

0.031

  1. Note: ACE angiotensin-converting enzyme, ACE2 angiotensin-converting enzyme-2, NEP neutral endopeptidase, APN aminopeptidase N, APA aminopeptidase A
  2. Values are medians of peptidase activity recorded as pmol of units of peptidase (UP) per milliliter of serum
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Biology of Sex Differences

ISSN: 2042-6410

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