Table 3 Interaction between loci controlling eosinophil numbers in the inguinal lymph nodes in L. major-infected F2 hybrids between CcS-9 and BALB/c
From: Gene-specific sex effects on eosinophil infiltration in leishmaniasis
D9Mit15 (Lmr26) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
CC | CS | SS | ||||||||
P = 3.7 × 10−2 | Corr. P = NS | % of expl. var. = NA | ||||||||
D11Nds10 (Lmr15) | CC | 4.24 | 1.236 | ±0.006 | 3.03 | 1.231 | ±0.004 | 2.19 | 1.226 | ±0.005 |
Both sexes | (n = 13) | (n = 26) | (n = 17) | |||||||
CS | 1.45 | 1.220 | ±0.004 | 3.76 | 1.235 | ±0.003 | 3.88 | 1.235 | ±0.003 | |
(n = 21) | (n = 63) | (n = 39) | ||||||||
SS | 2.56 | 1.229 | ±0.005 | 2.37 | 1.228 | ±0.004 | 3.36 | 1.233 | ±0.005 | |
(n = 17) | (n = 30) | (n = 16) | ||||||||
P = 0.67 | Corr. P = NS | % of expl. var. = NA | ||||||||
D11Nds10 (Lmr15) | CC | 1.89 | 1.224 | ±0.007 | 1.60 | 1.221 | ±0.004 | 1.42 | 1.219 | ±0.005 |
Females | (n = 6) | (n = 18) | (n = 10) | |||||||
Both crosses | CS | 1.37 | 1.219 | ±0.005 | 1.53 | 1.220 | ±0.003 | 2.28 | 1.227 | ±0.005 |
(n = 11) | (n = 38) | (n = 17) | ||||||||
SS | 1.67 | 1.222 | ±0.007 | 1.46 | 1.220 | ±0.004 | 1.06 | 1.214 | ±0.007 | |
(n = 7) | (n = 16) | (n = 6) | ||||||||
P = 2.63 × 10−4 | Corr. P = 1.037 × 10 −2 | % of expl. var. = 15.35 | ||||||||
D11Nds10 (Lmr15) | CC | 11.71 | 1.251 | ±0.010 | 12.05 | 1.251 | ±0.008 | 3.49 | 1.234 | ±0.008 |
Males | (n = 7) | (n = 8) | (n = 7) | |||||||
Both crosses | CS | 1.06 | 1.214 | ±0.007 | 23.15 | 1.260 | ±0.005 | 12.22 | 1.251 | ±0.004 |
(n = 10) | (n = 25) | (n = 22) | ||||||||
SS | 6.55 | 1.243 | ±0.008 | 5.18 | 1.239 | ±0.005 | 7.27 | 1.244 | ±0.007 | |
(n = 10) | (n = 14) | (n = 10) | ||||||||
P = 0.41 | Corr. P = NS | % of expl. var. = NA | ||||||||
D11Nds10 (Lmr15) | CC | 10.37 | 1.249 | ±0.008 | 12.60 | 1.252 | ±0.006 | 6.78 | 1.243 | ±0.008 |
Males | (n = 2) | (n = 2) | (n = 3) | |||||||
Cross CcS-9 × BALB | CS | 8.49 | 1.246 | ±0.022 | 21.20 | 1.258 | ±0.004 | 9.85 | 1.248 | ±0.007 |
(n = 2) | (n = 10) | (n = 10) | ||||||||
SS | 6.92 | 1.244 | ±0.012 | 3.75 | 1.235 | ±0.007 | 13.88 | 1.253 | ±0.022 | |
(n = 4) | (n = 4) | (n = 2) | ||||||||
P = 3.97 × 10−4 | Corr. P = 1.629 × 10 -2 | % of expl. var. = 21.19 | ||||||||
D11Nds10 (Lmr15) | CC | 44.01 | 1.267 | ±0.012 | 32.78 | 1.264 | ±0.010 | 8.88 | 1.247 | ±0.016 |
Males | (n = 5) | (n = 6) | (n = 4) | |||||||
Cross BALB × CcS-9 | CS | 0.47 | 1.199 | ±0.010 | 13.04 | 1.252 | ±0.006 | 12.40 | 1.252 | ±0.006 |
(n = 8) | (n = 15) | (n = 12) | ||||||||
SS | 9.73 | 1.248 | ±0.011 | 6.78 | 1.243 | ±0.007 | 4.84 | 1.238 | ±0.008 | |
(n = 6) | (n = 10) | (n = 8) | ||||||||