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Table 3 Interaction between loci controlling eosinophil numbers in the inguinal lymph nodes in L. major-infected F2 hybrids between CcS-9 and BALB/c

From: Gene-specific sex effects on eosinophil infiltration in leishmaniasis

  D9Mit15 (Lmr26)
CC CS SS
  P = 3.7 × 10−2 Corr. P = NS % of expl. var. = NA
D11Nds10 (Lmr15) CC 4.24 1.236 ±0.006 3.03 1.231 ±0.004 2.19 1.226 ±0.005
Both sexes     (n = 13)    (n = 26)    (n = 17)
CS 1.45 1.220 ±0.004 3.76 1.235 ±0.003 3.88 1.235 ±0.003
    (n = 21)    (n = 63)    (n = 39)
SS 2.56 1.229 ±0.005 2.37 1.228 ±0.004 3.36 1.233 ±0.005
    (n = 17)    (n = 30)    (n = 16)
  P = 0.67 Corr. P = NS % of expl. var. = NA
D11Nds10 (Lmr15) CC 1.89 1.224 ±0.007 1.60 1.221 ±0.004 1.42 1.219 ±0.005
Females     (n = 6)    (n = 18)    (n = 10)
Both crosses CS 1.37 1.219 ±0.005 1.53 1.220 ±0.003 2.28 1.227 ±0.005
    (n = 11)    (n = 38)    (n = 17)
SS 1.67 1.222 ±0.007 1.46 1.220 ±0.004 1.06 1.214 ±0.007
    (n = 7)    (n = 16)    (n = 6)
  P = 2.63 × 10−4 Corr. P = 1.037 × 10 −2   % of expl. var. = 15.35
D11Nds10 (Lmr15) CC 11.71 1.251 ±0.010 12.05 1.251 ±0.008 3.49 1.234 ±0.008
Males     (n = 7)    (n = 8)    (n = 7)
Both crosses CS 1.06 1.214 ±0.007 23.15 1.260 ±0.005 12.22 1.251 ±0.004
    (n = 10)    (n = 25)    (n = 22)
SS 6.55 1.243 ±0.008 5.18 1.239 ±0.005 7.27 1.244 ±0.007
    (n = 10)    (n = 14)    (n = 10)
  P = 0.41 Corr. P = NS % of expl. var. = NA
D11Nds10 (Lmr15) CC 10.37 1.249 ±0.008 12.60 1.252 ±0.006 6.78 1.243 ±0.008
Males     (n = 2)    (n = 2)    (n = 3)
Cross CcS-9 × BALB CS 8.49 1.246 ±0.022 21.20 1.258 ±0.004 9.85 1.248 ±0.007
    (n = 2)    (n = 10)    (n = 10)
SS 6.92 1.244 ±0.012 3.75 1.235 ±0.007 13.88 1.253 ±0.022
    (n = 4)    (n = 4)    (n = 2)
  P = 3.97 × 10−4 Corr. P = 1.629 × 10 -2 % of expl. var. = 21.19
D11Nds10 (Lmr15) CC 44.01 1.267 ±0.012 32.78 1.264 ±0.010 8.88 1.247 ±0.016
Males     (n = 5)    (n = 6)    (n = 4)
Cross BALB × CcS-9 CS 0.47 1.199 ±0.010 13.04 1.252 ±0.006 12.40 1.252 ±0.006
    (n = 8)    (n = 15)    (n = 12)
SS 9.73 1.248 ±0.011 6.78 1.243 ±0.007 4.84 1.238 ±0.008
    (n = 6)    (n = 10)    (n = 8)
  1. Mean and SE values were obtained by analysis of variance. In order to obtain normal distribution required for analysis of variance value of eosinophil numbers in serum inguinal lymph nodes was transformed by using the 0.1th power of natural logarithm of the (observed value ×1000). The numbers in bold give the average non-transformed values. C and S indicate the presence of BALB/c and STS allele, respectively
  2. n number of mice