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Table 1 Mesor (average), amplitude and acrophase of MAP, heart rate, and locomotor activity in male and female C57BL6 mice at 3, 5, 14, and 18 months (Mo) of age over a 24-h cycle time (CT; midnight to midnight) following cosinar analysis

From: Sex- and age-related differences in arterial pressure and albuminuria in mice

  M 3-Mo F 3-Mo M 5-Mo F 5-Mo M 14-Mo F 14-Mo M 18-Mo F 18-Mo
n 12 11 11 7 12 10 12 8
MAP
 Mesor (mmHg) 95 ± 1 90 ± 1* 98 ± 1 91 ± 1* 101 ± 1# 93 ± 1** 101 ± 1# 98 ± 1##
 Amplitude (mmHg) 9 ± 1 7 ± 1 9 ± 1 6 ± 1 9 ± 1 8 ± 1 9 ± 1 9 ± 1
Acrophase, CT (h) 22.2 ± 0.8 22.5 ± 0.8 23.5 ± 1.0 22.0 ± 0.8 22.6 ± 21.0 ± 1.8 23.7 ± 0.8 23.4 ± 1.1
HR
 Mesor (bpm) 473 ± 14 539 ± 11* 514 ± 14 546 ± 19 549 ± 11## 567 ± 10 535 ± 16# 607 ± 17*##
 Amplitude (bpm) 64 ± 8 48 ± 4 70 ± 7 52 ± 5 63 ± 6 58 ± 6 77 ± 9 52 ± 9
 Acrophase, CT (h) 21.3 ± 0.6 21.8 ± 1.6 20.5 ± 0.6 20.7 ± 0.7 21.0 ± 0.9 20.7 ± 0.7 22.4 ± 1.0 20.3 ± 0.7
Activity
 Mesor (units) 4.9 ± 0.3 5.8 ± 0.6 4.4 ± 0.4 4.1 ± 0.6 3.5 ± 0.4 5.3 ± 0.6 3.4 ± 0.4 5.9 ± 1.2
 Amplitude (units) 3.3 ± 0.4 3.6 ± 0.6 3.2 ± 0.4 2.3 ± 0.6 2.0 ± 0.4 3.5 ± 0.6 2.0 ± 0.4 3.1 ± 0.7
 Acrophase, CT (h) 20.6 ± 1.5 22.3 ± 0.9 21.8 ± 1.0 18.5 ± 2.2 18.5 ± 1.9 21.9 ± 1.2 19.3 ± 2.2 21.5 ± 1.0
  1. *P < 0.05, **P < 0.01 compared to age-matched males; # P < 0.05, ## P < 0.01 as compared to 3 months of age in the same sex