Table 1 Mesor (average), amplitude and acrophase of MAP, heart rate, and locomotor activity in male and female C57BL6 mice at 3, 5, 14, and 18Â months (Mo) of age over a 24-h cycle time (CT; midnight to midnight) following cosinar analysis
From: Sex- and age-related differences in arterial pressure and albuminuria in mice
| Â | M 3-Mo | F 3-Mo | M 5-Mo | F 5-Mo | M 14-Mo | F 14-Mo | M 18-Mo | F 18-Mo |
|---|---|---|---|---|---|---|---|---|
n | 12 | 11 | 11 | 7 | 12 | 10 | 12 | 8 |
MAP | ||||||||
 Mesor (mmHg) | 95 ± 1 | 90 ± 1* | 98 ± 1 | 91 ± 1* | 101 ± 1# | 93 ± 1** | 101 ± 1# | 98 ± 1## |
 Amplitude (mmHg) | 9 ± 1 | 7 ± 1 | 9 ± 1 | 6 ± 1 | 9 ± 1 | 8 ± 1 | 9 ± 1 | 9 ± 1 |
Acrophase, CT (h) | 22.2 ± 0.8 | 22.5 ± 0.8 | 23.5 ± 1.0 | 22.0 ± 0.8 | 22.6 ± | 21.0 ± 1.8 | 23.7 ± 0.8 | 23.4 ± 1.1 |
HR | ||||||||
 Mesor (bpm) | 473 ± 14 | 539 ± 11* | 514 ± 14 | 546 ± 19 | 549 ± 11## | 567 ± 10 | 535 ± 16# | 607 ± 17*## |
 Amplitude (bpm) | 64 ± 8 | 48 ± 4 | 70 ± 7 | 52 ± 5 | 63 ± 6 | 58 ± 6 | 77 ± 9 | 52 ± 9 |
 Acrophase, CT (h) | 21.3 ± 0.6 | 21.8 ± 1.6 | 20.5 ± 0.6 | 20.7 ± 0.7 | 21.0 ± 0.9 | 20.7 ± 0.7 | 22.4 ± 1.0 | 20.3 ± 0.7 |
Activity | ||||||||
 Mesor (units) | 4.9 ± 0.3 | 5.8 ± 0.6 | 4.4 ± 0.4 | 4.1 ± 0.6 | 3.5 ± 0.4 | 5.3 ± 0.6 | 3.4 ± 0.4 | 5.9 ± 1.2 |
 Amplitude (units) | 3.3 ± 0.4 | 3.6 ± 0.6 | 3.2 ± 0.4 | 2.3 ± 0.6 | 2.0 ± 0.4 | 3.5 ± 0.6 | 2.0 ± 0.4 | 3.1 ± 0.7 |
 Acrophase, CT (h) | 20.6 ± 1.5 | 22.3 ± 0.9 | 21.8 ± 1.0 | 18.5 ± 2.2 | 18.5 ± 1.9 | 21.9 ± 1.2 | 19.3 ± 2.2 | 21.5 ± 1.0 |