Fig. 6

Body weight, organ weights, and albuminuria in male (blue bars) and female (red bars) mice at 3, 5, 14, and 18 months of age. a Body weight (BW), b heart weight, c heart weight to BW ratio, d total kidney weight, e total kidney weight to BW ratio, and f albuminuria. Data were analyzed using a 2-way ANOVA with the factors sex, age and their interaction. Tukey post hoc tests were performed where appropriate. *P < 0.05, **P < 0.01, ****P < 0.0001 as compared to age-matched male. ^# P < 0.05, ^## P < 0.01, ^### P < 0.001, ^#### P < 0.0001 as compared to the 3-month-old counterpart. ^† P < 0.05, ^†† P < 0.01, ^††† P < 0.001, ^†††† P < 0.001 as compared to the 5-month-old counterpart. ^§P < 0.05, ^§§P < 0.01, ^§§§§P < 0.0001 as compared to the 14-month-old counterpart