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Table 1 Androgen-regulated miRNAs and their corresponding mRNA target(s) on GD 17.0 classified according to several biological processes

From: Expression profile of androgen-modulated microRNAs in the fetal murine lung

Biological process Gestational day 17.0
miRNA mRNA target
Lipid metabolic process mmu-miR-3078 Etnk1; Pafah1b2
  mmu-miR-877 Elovl4; Etnk1
  mmu-miR-449a Pdgfra
  mmu-miR-1955-5p Hdlbp; Pik3r1
  mmu-miR-126-5p Pbx1
  mmu-miR-362-3p Pbx1
  mmu-miR-3470b Smg1
  mmu-let-7f-2-3p Col4a3bp; Etnk1
  mmu-let-7b-3p Col4a3bp
  mmu-miR-1249-5p Smg1
  mmu-miR-92a-1-5p Hdlbp
Developmental programmed cell death mmu-miR-449a Slc4a7
Cell proliferation mmu-miR-1306-5p Zeb2
  mmu-miR-1955-5p Gng2
  mmu-miR-215 Igf1; Zeb2
  mmu-miR-126-5p Mmp16; Igf1; Yap1
  mmu-let-7f-2-3p Col4a3bp
  mmu-let-7b-3p Col4a3bp
  mmu-miR-674-3p Mmp16
Intracellular estrogen receptor signaling pathway mmu-miR-126-5p Arid1a
  mmu-miR-3103-5p Arid1a
Androgen receptor signaling pathway mmu-miR-126-5p Arid1a
  mmu-miR-3103-5p Arid1a
Lung cell differentiation mmu-miR-3078 Creb1
  mmu-miR-126-5p Igf1
  mmu-miR-215 Igf2
  mmu-miR-687 Nfib
Cell-cell signaling mmu-miR-3078 Gabra1; Gja1
  mmu-miR-1306-5p Gja1
  mmu-let-7f-2-3p Gabra1
Lung development mmu-miR-126-5p Igf1
  mmu-miR-215 Igf1
  mmu-miR-687 Nfib
  mmu-miR-449a Pdgfra
  mmu-miR-3078 Zfpm2; Creb1
Wnt signaling pathway mmu-miR-687 Apc
  mmu-miR-3089-3p Tnks2
  mmu-miR-1843-5p Sfrp1
  mmu-miR-449a Tbl1xr1
  mmu-miR-3078 Tle4
  mmu-miR-1195 Tnks2
  mmu-miR-1249-5p Sfrp1
  mmu-let-7b-3p Tle4
Steroid metabolic process mmu-miR-1955-5p Hdlbp
  mmu-miR-126-5p Pbx1
  mmu-miR-449a Pdgfra
  mmu-miR-92a-1-5p Hdlbp
Corticosteroid receptor signaling pathway mmu-miR-126-5p Arid1a
  mmu-miR-3103-5p Arid1a
Angiogenesis mmu-miR-362-3p Naa15
  mmu-miR-467h Map3k7
  mmu-miR-669i Map3k7
  mmu-miR-1955-5p Naa15
  mmu-miR-3078 Naa15
  mmu-miR-687 Naa15
Notch signaling pathway mmu-miR-687 Adam10
  mmu-miR-3078 Adam17
  mmu-miR-3089-3p Adam17
  mmu-miR-362-3p Adam17
  mmu-miR-126-5p Jag1
  mmu-miR-449a Jag1
  mmu-let-7b-3p Jag1
Transforming growth factor beta receptor signaling pathway mmu-miR-3078 Creb1
  mmu-miR-467h Map3k7
  mmu-miR-669i Map3k7
Fibroblast growth factor receptor signaling pathway mmu-miR-149 Ndst1
Platelet-derived growth factor receptor signaling pathway mmu-miR-449a Pdgfra
  mmu-miR-3089-3p Zfand5
  mmu-miR-126-5p Zfand5
  1. Italicized data are upregulated by flutamide; boldface data are downregulated by flutamide