Table 1 Androgen-regulated miRNAs and their corresponding mRNA target(s) on GD 17.0 classified according to several biological processes
From: Expression profile of androgen-modulated microRNAs in the fetal murine lung
Biological process | Gestational day 17.0 | |
|---|---|---|
miRNA | mRNA target | |
Lipid metabolic process | mmu-miR-3078 | Etnk1; Pafah1b2 |
| Â | mmu-miR-877 | Elovl4; Etnk1 |
| Â | mmu-miR-449a | Pdgfra |
| Â | mmu-miR-1955-5p | Hdlbp; Pik3r1 |
| Â | mmu-miR-126-5p | Pbx1 |
| Â | mmu-miR-362-3p | Pbx1 |
| Â | mmu-miR-3470b | Smg1 |
| Â | mmu-let-7f-2-3p | Col4a3bp; Etnk1 |
| Â | mmu-let-7b-3p | Col4a3bp |
| Â | mmu-miR-1249-5p | Smg1 |
| Â | mmu-miR-92a-1-5p | Hdlbp |
Developmental programmed cell death | mmu-miR-449a | Slc4a7 |
Cell proliferation | mmu-miR-1306-5p | Zeb2 |
| Â | mmu-miR-1955-5p | Gng2 |
| Â | mmu-miR-215 | Igf1; Zeb2 |
| Â | mmu-miR-126-5p | Mmp16; Igf1; Yap1 |
| Â | mmu-let-7f-2-3p | Col4a3bp |
| Â | mmu-let-7b-3p | Col4a3bp |
| Â | mmu-miR-674-3p | Mmp16 |
Intracellular estrogen receptor signaling pathway | mmu-miR-126-5p | Arid1a |
| Â | mmu-miR-3103-5p | Arid1a |
Androgen receptor signaling pathway | mmu-miR-126-5p | Arid1a |
| Â | mmu-miR-3103-5p | Arid1a |
Lung cell differentiation | mmu-miR-3078 | Creb1 |
| Â | mmu-miR-126-5p | Igf1 |
| Â | mmu-miR-215 | Igf2 |
| Â | mmu-miR-687 | Nfib |
Cell-cell signaling | mmu-miR-3078 | Gabra1; Gja1 |
| Â | mmu-miR-1306-5p | Gja1 |
| Â | mmu-let-7f-2-3p | Gabra1 |
Lung development | mmu-miR-126-5p | Igf1 |
| Â | mmu-miR-215 | Igf1 |
| Â | mmu-miR-687 | Nfib |
| Â | mmu-miR-449a | Pdgfra |
| Â | mmu-miR-3078 | Zfpm2; Creb1 |
Wnt signaling pathway | mmu-miR-687 | Apc |
| Â | mmu-miR-3089-3p | Tnks2 |
| Â | mmu-miR-1843-5p | Sfrp1 |
| Â | mmu-miR-449a | Tbl1xr1 |
| Â | mmu-miR-3078 | Tle4 |
| Â | mmu-miR-1195 | Tnks2 |
| Â | mmu-miR-1249-5p | Sfrp1 |
| Â | mmu-let-7b-3p | Tle4 |
Steroid metabolic process | mmu-miR-1955-5p | Hdlbp |
| Â | mmu-miR-126-5p | Pbx1 |
| Â | mmu-miR-449a | Pdgfra |
| Â | mmu-miR-92a-1-5p | Hdlbp |
Corticosteroid receptor signaling pathway | mmu-miR-126-5p | Arid1a |
| Â | mmu-miR-3103-5p | Arid1a |
Angiogenesis | mmu-miR-362-3p | Naa15 |
| Â | mmu-miR-467h | Map3k7 |
| Â | mmu-miR-669i | Map3k7 |
| Â | mmu-miR-1955-5p | Naa15 |
| Â | mmu-miR-3078 | Naa15 |
| Â | mmu-miR-687 | Naa15 |
Notch signaling pathway | mmu-miR-687 | Adam10 |
| Â | mmu-miR-3078 | Adam17 |
| Â | mmu-miR-3089-3p | Adam17 |
| Â | mmu-miR-362-3p | Adam17 |
| Â | mmu-miR-126-5p | Jag1 |
| Â | mmu-miR-449a | Jag1 |
| Â | mmu-let-7b-3p | Jag1 |
Transforming growth factor beta receptor signaling pathway | mmu-miR-3078 | Creb1 |
| Â | mmu-miR-467h | Map3k7 |
| Â | mmu-miR-669i | Map3k7 |
Fibroblast growth factor receptor signaling pathway | mmu-miR-149 | Ndst1 |
Platelet-derived growth factor receptor signaling pathway | mmu-miR-449a | Pdgfra |
| Â | mmu-miR-3089-3p | Zfand5 |
| Â | mmu-miR-126-5p | Zfand5 |