Table 1 Androgen-regulated miRNAs and their corresponding mRNA target(s) on GD 17.0 classified according to several biological processes
From: Expression profile of androgen-modulated microRNAs in the fetal murine lung
| Biological process | Gestational day 17.0 | |
|---|---|---|
| miRNA | mRNA target | |
| Lipid metabolic process | mmu-miR-3078 | Etnk1; Pafah1b2 |
| mmu-miR-877 | Elovl4; Etnk1 | |
| mmu-miR-449a | Pdgfra | |
| mmu-miR-1955-5p | Hdlbp; Pik3r1 | |
| mmu-miR-126-5p | Pbx1 | |
| mmu-miR-362-3p | Pbx1 | |
| mmu-miR-3470b | Smg1 | |
| mmu-let-7f-2-3p | Col4a3bp; Etnk1 | |
| mmu-let-7b-3p | Col4a3bp | |
| mmu-miR-1249-5p | Smg1 | |
| mmu-miR-92a-1-5p | Hdlbp | |
| Developmental programmed cell death | mmu-miR-449a | Slc4a7 |
| Cell proliferation | mmu-miR-1306-5p | Zeb2 |
| mmu-miR-1955-5p | Gng2 | |
| mmu-miR-215 | Igf1; Zeb2 | |
| mmu-miR-126-5p | Mmp16; Igf1; Yap1 | |
| mmu-let-7f-2-3p | Col4a3bp | |
| mmu-let-7b-3p | Col4a3bp | |
| mmu-miR-674-3p | Mmp16 | |
| Intracellular estrogen receptor signaling pathway | mmu-miR-126-5p | Arid1a |
| mmu-miR-3103-5p | Arid1a | |
| Androgen receptor signaling pathway | mmu-miR-126-5p | Arid1a |
| mmu-miR-3103-5p | Arid1a | |
| Lung cell differentiation | mmu-miR-3078 | Creb1 |
| mmu-miR-126-5p | Igf1 | |
| mmu-miR-215 | Igf2 | |
| mmu-miR-687 | Nfib | |
| Cell-cell signaling | mmu-miR-3078 | Gabra1; Gja1 |
| mmu-miR-1306-5p | Gja1 | |
| mmu-let-7f-2-3p | Gabra1 | |
| Lung development | mmu-miR-126-5p | Igf1 |
| mmu-miR-215 | Igf1 | |
| mmu-miR-687 | Nfib | |
| mmu-miR-449a | Pdgfra | |
| mmu-miR-3078 | Zfpm2; Creb1 | |
| Wnt signaling pathway | mmu-miR-687 | Apc |
| mmu-miR-3089-3p | Tnks2 | |
| mmu-miR-1843-5p | Sfrp1 | |
| mmu-miR-449a | Tbl1xr1 | |
| mmu-miR-3078 | Tle4 | |
| mmu-miR-1195 | Tnks2 | |
| mmu-miR-1249-5p | Sfrp1 | |
| mmu-let-7b-3p | Tle4 | |
| Steroid metabolic process | mmu-miR-1955-5p | Hdlbp |
| mmu-miR-126-5p | Pbx1 | |
| mmu-miR-449a | Pdgfra | |
| mmu-miR-92a-1-5p | Hdlbp | |
| Corticosteroid receptor signaling pathway | mmu-miR-126-5p | Arid1a |
| mmu-miR-3103-5p | Arid1a | |
| Angiogenesis | mmu-miR-362-3p | Naa15 |
| mmu-miR-467h | Map3k7 | |
| mmu-miR-669i | Map3k7 | |
| mmu-miR-1955-5p | Naa15 | |
| mmu-miR-3078 | Naa15 | |
| mmu-miR-687 | Naa15 | |
| Notch signaling pathway | mmu-miR-687 | Adam10 |
| mmu-miR-3078 | Adam17 | |
| mmu-miR-3089-3p | Adam17 | |
| mmu-miR-362-3p | Adam17 | |
| mmu-miR-126-5p | Jag1 | |
| mmu-miR-449a | Jag1 | |
| mmu-let-7b-3p | Jag1 | |
| Transforming growth factor beta receptor signaling pathway | mmu-miR-3078 | Creb1 |
| mmu-miR-467h | Map3k7 | |
| mmu-miR-669i | Map3k7 | |
| Fibroblast growth factor receptor signaling pathway | mmu-miR-149 | Ndst1 |
| Platelet-derived growth factor receptor signaling pathway | mmu-miR-449a | Pdgfra |
| mmu-miR-3089-3p | Zfand5 | |
| mmu-miR-126-5p | Zfand5 | |
