Skip to main content

Table 5 Two-way ANOVA for univariate and pairwise comparisons between gender, estrous cycle stages, and exposure for STAT3 Serine 727 phosphorylation expression

From: Sex-specific IL-6-associated signaling activation in ozone-induced lung inflammation

Univariate tests: dependent variable: STAT3 Serine 727
    df F Sig. Partial η2
Analysis of gender and exposure Exposure FA 1, 60 0.001 1.000 0.002
Ozone 1,60 27.137 <0.0005 0.311
Sex F 1, 60 17.209 <0.0005 0.223
M 1, 60 1.126 0.293 0.018
Analysis of female estrous cycle stages and exposure Estrous cycle stage Non-proestrus 1, 28 2.282 0.142 0.075
Proestrus 1, 28 53.117 <0.0005 0.655
Exposure FA 1, 28 9.535 0.005 0.254
Ozone 1, 28 141.295 <.0005 0.835
Pairwise comparisons: dependent variable: STAT3 Serine 727
    (I) Sex (J) Sex Mean difference (I–J) 95 % CI for difference
Lower bound Upper bound
Analysis of gender and exposure Exposure FA F M 2.500E-8 0.388 0.388
Ozone F M 1.009 0.622 1.397
Sex F Ozone FA 0.804 0.416 1.191
M FA Ozone 0.206 0.182 0.593
Analysis of female estrous cycle stages and exposure Estrous cycle stage Non-proestrus FA Ozone 0.254 0.090 0.597
Proestrus Ozone FA 1.223 0.880 1.567
Exposure FA Proestrus Non-proestrus 0.518 0.174 0.862
Ozone Proestrus Non-proestrus 1.995 1.652 2.339