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Fig. 1 | Biology of Sex Differences

Fig. 1

From: High-fat diet impairs spatial memory and hippocampal intrinsic excitability and sex-dependently alters circulating insulin and hippocampal insulin sensitivity

Fig. 1

The spontaneous alternation task used to assess spatial memory. a A four-arm radial plus maze, with two explicit distal visual cues for spatial orientation. No explicit rewards were present on the maze. b The time line used to ensure the behavior of all rats was minimally impacted by stressors related to the environment or the experimenters. c Parsing of exploratory behavior into sets of alternations or non-alternations. d Conversion of raw behavioral observations into % alternation scores for comparisons between individuals and between groups

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