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Fig. 4 | Biology of Sex Differences

Fig. 4

From: Perinatal testosterone exposure is critical for the development of the male-specific sexually dimorphic gastrin-releasing peptide system in the lumbosacral spinal cord that mediates erection and ejaculation

Fig. 4

Neonatal castration demasculinizes the spinal GRP system. Effects of the androgen surge on neonatal development of the spinal GRP system in males (left panels). Immunohistochemical analysis of GRP (green) and nNOS (magenta) expression showed that the intensity of GRP-immunoreactive fibers in the SPN was decreased by neonatal orchiectomy (ORX) but was prevented by administering testosterone propionate (TP) (ORX + TP) to neonates. Arrowheads indicate possible GRP-positive cell bodies. Scale bars 100 μm, left panel; 50 μm, right panel

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Biology of Sex Differences

ISSN: 2042-6410

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