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Table 3 Cell-derived blood-borne microvesicles from apparently healthy women and men separated by age, sex, and menopausal status

From: Age- and sex-specific differences in blood-borne microvesicles from apparently healthy humans

Blood-borne microvesicles 20–70 years old 20–65 years old 51–70 years old
Women ( N= 82) Men ( N= 62) Premenopausal women ( N= 58) Men ( N= 59) Postmenopausal women ( N= 24) Men ( N= 33)
Cellular origin of MV/μL plasma
Total erythrocyte-(CD235a) derived MV 57 (23, 107) 73 (44, 124) 49* (19, 96) 76 (45, 142) 77 (50, 177) 69 (40, 165)
Total leukocyte (CD45)-derived MV 23 (16, 35) 23 (17, 38) 23 (16, 38) 23 (17, 39) 28 (16, 35) 25 (18, 41)
Monocyte (CD14)-derived MV 12 (7, 27) 11 (6, 26) 12 (7, 27) 11 (6, 25) 12 (6, 27) 16 (8, 38)
T-cell (CD3)-derived MV 6 (4, 9) 5 (3, 9) 6 (4, 9) 5 (3, 10) 6 (4, 13) 5 (3, 7)
B-cell (CD19)-derived MV 10 (5, 16) 7 (4, 17) 8 (4, 15) 7 (4, 17) 11 (6, 23) 7 (4, 19)
Platelet (CD42a)-derived MV 626* (293, 1156) 486 (342, 868) 687 (261, 1126) 492 (349, 853) 529 (362, 1298) 508 (364, 921)
Endothelium (CD62E)-derived MV 17* (9, 30) 10 (4, 22) 16* (7, 24) 10 (5, 22) 20* (11, 41) 9 (5, 21)
Adipocyte (FABP4)-derived MV 5 (3, 15) 5 (2, 10) 5 (3, 14) 5 (1, 10) 5 (2, 18) 6 (3, 14)
Stem/progenitor cell (CD117)-derived MV 4 (2, 8) 6 (3, 10) 3* (2, 7) 6 (3, 10) 5 (3, 8) 7 (5, 10)
Senescent cell (p16-set)-derived MV 7 (3, 13) 5 (2, 12) 7 (3, 14) 5 (2, 12) 6 (2, 12) 6 (2, 18)
  1. Data are presented as median with 25th and 75th percentiles.
  2. *Statistically significant (P < 0.05) differences in concentration of MV between women and age-matched men. Statistically significant (P < 0.05) differences in concentration of MV between postmenopausal women and premenopausal women.