Figure 11
Dsx is a regulator of sex-specific gene expression in the A. aegypti pupal brain. Sex specific patterns of p53 (A), synj (B), geko (C), cdk4/6 (D), and rab6 (E) mRNA transcripts were detected in female (upper portion of each panel) and male (lower portion of each panel) wild-type and control-fed 24 h pupal brain hemisegments, which are oriented dorsal upward in each panel. The position of the optic lobe is marked by an asterisk in (A) and located at a similar position in the other panels. The sex-specific expression patterns of each gene were disrupted following injection of either dsx KD A or KD B siRNAs.