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Table 1 Global parameters of the left ventricle in shame and MI hearts from male (M) and female (F) rats

From: Coronary vessels and cardiac myocytes of middle-aged rats demonstrate regional sex-specific adaptation in response to postmyocardial infarction remodeling

  M-Sham M-MI F-Sham F-MI
Number 7 7 6 6
Infarct size, % of LVFW - 61.5 ± 1.2 (57.5–63.8) - 61.3 ± 3.9 (50.0–71.3)
BW, g 560.0 ± 15.4 536.8 ± 27.2 362.5 ± 6.4§§§ 335.7 ± 21.5†††
VW, mg 1476.4 ± 39.7 1461.8 ± 88.2 1214.5 ± 50.6§ 1084.2 ± 16.6†††
LVW, mg 1150.4 ± 33.4 1100.4 ± 55.2 935.2 ± 46.0§§ 829.5 ± 12.2†††
RVW, mg 326.0 ± 9.6 361.4 ± 40.5 279.3 ± 5.6 254.7 ± 18.3
LVW/BW, mg/g 2.06 ± 0.08 2.05 ± 0.07 2.58 ± 0.09§ 2.52 ± 0.15
LVW/VW, mg/mg 0.78 ± 0.01 0.76 ± 0.02 0.77 ± 0.01 0.77 ± 0.01
LV diameter, mm 11.06 ± 0.09 11.03 ± 0.25 9.89 ± 0.24§ 9.88 ± 0.19††
LV CSA, mm2 96.9 ± 1.6 96.5 ± 4.3 78.3 ± 4.0§ 78.4 ± 3.1
LV cavity diameter, mm 6.33 ± 0.30 7.58 ± 0.22* 5.82 ± 0.34 6.61 ± 0.44
LV cavity CSA, mm2 32.9 ± 2.9 46.4 ± 2.7* 27.9 ± 3.1 36.4 ± 4.5
LVFW thickness, mm 2.31 ± 0.13 2.29 ± 0.11 1.92 ± 0.10 2.12 ± 0.21
Septum thickness, mm 1.75 ± 0.09 1.77 ± 0.12 1.64 ± 0.08 1.68 ± 0.11
LV cavity diameter/septum 3.67 ± 0.30 4.39 ± 0.35 3.60 ± 0.30 4.02 ± 0.44
Remodeling index - 1.39 ± 0.09 - 1.41 ± 0.11
  1. Values are the mean ± SEM; n, Number of rats; LVFW, left ventricular free wall; BW, body weight; VW, ventricular weight; LVW, left ventricular weight; RVW, right ventricular weight; CSA, cross-sectional area. Remodeling index = (LV cavity CSA of MI heart/Average LV cavity CSA of sham hearts) × (LVFW thickness of MI heart/Average LVFW thickness of sham hearts). *P < 0.05 vs. corresponding Sham group; §P < 0.05, §§P < 0.01, and §§§P < 0.001 vs. M-Sham; P < 0.05, ††P < 0.01, and †††P < 0.001 vs. M-MI.