Figure 4

Scale of adaptive arteriogenesis. (A,B) Representative images of the LV free wall myocardium of post-MI male and female rats immunofluorescence-stained with an antibody against smooth muscle α-actin (red color) and DAPI (blue). (C) Arteriolar length density relative to a vessel diameter group in the LV free wall and septum. (D) Arteriolar volume density relative to a vessel diameter group in the LV free wall and septum. Scale bars are 20 μm. Values are the mean ± SEM; n = 7 male rats/group; n = 6 female rats/group. ^*P < 0.05 vs. a corresponding sham group; ^§§P < 0.01 and ^§§§P < 0.001 vs. M-Sham rats; ^†P < 0.05 and ^†††P < 0.001 vs. M-MI rats.