Figure 3
Renal pathology of male and female NZB/W F1 mice. Renal sections from 23-wk-old and 30-wk-old male and female NZB/WF1 mice were stained with H&E and PAS, respectively. Representative images from each age and gender group were shown. Note that only the 30-wk-old female NZB/WF1 mice demonstrated moderate to severe mesangioproliferative glomerulonephritis and tubular protein casts (indicated by arrow). The mice in the other groups showed no or minimal glomerular inflammation.