Figure 6

Motor performance. (A) In the challenging beam test, gonadal males took 38% longer to cross the beam compared to females (F(1,85) = 12.45, p = 0.0007, overall ANOVA) XX gonadal males took longer to cross the beam than XY males, but XX and XY females did not differ (F(1,53) = 4.60, p = 0.037, *INT). (B) Gonadal males took 7% more steps to cross the beam compared to gonadal females (F(1,85) = 4.41, p = 0.04, overall ANOVA), but the effect of sex depended on the genotype (F(3,85) = 7.02, p = 0.0003, *INT). In pairwise comparisons, the difference between XY and XX, and XY and XYY, depended on sex (F(1,53) = 5.25, p = 0.026 and F(1,46) = 4.78, p = 0.034, respectively, *INT). (C) In time to turn on the pole, the difference between XY and XYY mice depended on their sex (F(1,46) = 6.80, p = 0.012, *INT). (D) In time to complete the pole test, the difference between XY and XYY mice depended on their sex (F(1,46) = 4.62, p = 0.037, *INT). *INT indicates significant interactions of gonadal sex and sex chromosome complement. Values are mean ± SEM.