Figure 5

Tissue weights after gonadectomy and treatment with testosterone. All tissue weights except spleen were greater in gonadal males than females in the overall ANOVA (liver, F(1,85) = 13.05, *p = 0.0005; inguinal fat, F(1,86) = 19.41, *p = 0.00003; gonadal fat, F(1,50) = 23.29, *p = 0.00001; kidney, F(1,86) = 7.28, *p = 0.008), and sex chromosome complement affected liver weight in the overall ANOVA (F(3,85) = 3.84, *p = 0.012). XXY mice had heavier livers (A), and gonadal (B) and inguinal (C) fat pads, compared to XY (liver, F(1,51) = 8.13, *p = 0.006; gonadal fat F(1,29) = 7.61, *p = 0.01; inguinal fat, F(1,51) = 4.55, *p = 0.038). There were no group differences in spleen (D) weights. Values are mean ± SEM.