Figure 6
From: Sex differences matter in the gut: effect on mucosal immune activation and inflammation
The activation profile seen in peripheral blood and gut is matched by the increase in transcription of activation and inflammation associated genes (CCL5/ RANTES, IFNγ, TNSF10 and TNFα, IL1β) in CD4+ T cells of women compared to men. Real Time PCR analysis of CD4+ T cells enriched from the PBMC and LPL of women showed a significant increase in transcription of proinflammatory factors such as CCL5 (A), IFNγ (B), IL1β (C), TNSF10 (D), and TNFα (E). (* = p<.05).