Figure 1

BMPR2 expression is lower in female humans and mice than males. (A) BMPR2 expression by quantitative RT-PCR, normalized to HPRT, is reduced in cultured human lymphocytes from females compared with males. (B) BMPR2 expression normalized to HPRT is lower in whole lung from ovariectomized female mice compared with males. (C) ERα and ERβ expression are both higher in whole lung from ovariectomized female mice compared with males. All comparisons were by unpaired Student's t-test.