Figure 5

MFI shows sex differences in TLR4 protein expression on lymphocyte populations. Male mice have greater levels of TLR4 expression on CD3+, F480+ and CD11c+ cells at all three timepoints (p=<0.001 for all values). In addition, male CD4+ cells have higher levels of TLR4 at both Day 3 (p=0.039) and Day 6 (p=0.011) compared to females. Numbers of mice used in this experiment were as follows: Male D6=6, D3=3, D0=3; Female D6=5, D3=4, D0=5.