Table 5 Plasma follistatin and myostatin concentrations and muscle myoD, myostatin, and follistatin gene expression in young and old men and women
From: Sexually dimorphic effect of aging on skeletal muscle protein synthesis
| Â | MEN | WOMEN | ANOVA | ||||
|---|---|---|---|---|---|---|---|
| Â | Young | Old | Young | Old | Sex | Age | Interaction |
Plasma (ng/mL) | |||||||
Myostatin | 3.12 ± 0.30 | 3.36 ± 0.24 | 3.29 ± 0.34 | 3.54 ± 0.42 | 0.61 | 0.47 | 0.99 |
Follistatin | 1.58 ± 0.12 | 1.87 ± 0.12 | 1.22 ± 0.08 | 1.81 ± 0.12 | 0.07 | 0.005 | 0.19 |
Muscle mRNA (arbitrary units) | |||||||
Myostatin | 1.00 ± 0.28 | 0.73 ± 0.17 | 0.82 ± 0.12 | 0.95 ± 0.17 | 0.92 | 0.70 | 0.28 |
Follistatin | 1.00 ± 0.32 | 0.68 ± 0.19 | 1.40 ± 0.46 | 1.55 ± 0.59 | 0.15 | 0.85 | 0.58 |
MyoD | 1.00 ± 0.39 | 1.21 ± 0.21 | 1.26 ± 0.38 | 1.12 ± 0.28 | 0.68 | 0.97 | 0.68 |