Myocarditis and cardiac virus titers in four core genotype (FCG) mice infected with coxsackievirus B3 (CVB3). FCG mice were gonadectomized (Gdx) and infected with 100 plaque-forming units (PFU) CVB3. Surviving mice were killed 7 days after infection and evaluated for (a) myocarditis using a 0-4 histology scale and for (b) cardiac virus titer (PFU log10/g tissue). Results represent mean ± SEM of 10-13 mice/group. *Significantly different at P < 0.05.