Figure 4
From: Sex differences in the inflammatory response of primary astrocytes to lipopolysaccharide
Astrocytes from control and androgenized females show a different response to LPS. mRNA levels of IL6, IP10, TNFα and IL1β in LPS-treated cortical astrocyte cultures from female mouse pups injected with oil (Oil+LPS) and from female mouse pups treated with testosterone propionate (TP+LPS). Data are means ± SEM and are expressed as percentages of control values (red line indicates astrocytes cultured with control medium without LPS). ***P < 0.001, indicating significant differences compared with values of female mouse pups treated with oil. +++P < 0.001, indicating significant differences compared with cultures not treated with LPS.