Figure 2From: The innate immune response to coxsackievirus B3 predicts progression to cardiovascular disease and heart failure in male mice Verification of genes increased in males compared to females prior to infection. Gene changes between uninfected males (Un-M) and uninfected females (Un-F) in Table 2 were verified by quantitative real-time polymerase chain reaction. Genes increased in males included: cyclin E2 (Ccne2); Cyp2e1; carbonic anhydrase 3 (Ca3); aldehyde dehydrogenase (Aldh1a7); sulphotransferase1e1 (Sult1e1); haptoglobin (Hp); and heat shock protein 90 (Hsp90aa1). Relative gene expression (RGE) normalized to hypoxanthine phosphoribosyltransferase (HPRT) is shown as the mean ± standard error of the mean of seven mice per group. *, P < 0.05; **, P < 0.01; ***, P < 0.001.Back to article page