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Fig. 6 | Biology of Sex Differences

Fig. 6

From: TrkB-mediated neuroprotection in female hippocampal neurons is autonomous, estrogen receptor alpha-dependent, and eliminated by testosterone: a proposed model for sex differences in neonatal hippocampal neuronal injury

Fig. 6

A model of female-specific neuroprotection in hippocampal neurons Hypoxia leads to increases in the ERα expression and responsiveness to 7,8-DHF in female hippocampal neurons. The resulting increase in TrkB phosphorylation promotes cell survival pathways in these cells. Pre-treatment with T blocks this pathway in a manner that has yet to be determined

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Biology of Sex Differences

ISSN: 2042-6410

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