Fig. 4From: Endothelin mediates sex-differences in acclimation to high salt diet in ratsDual ET receptor antagonism increased blood pressure in both male and female rats. Mean arterial blood pressure measured in NS or HS-fed male and female rats treated with and without the dual ET receptor antagonist (A-182086, 10 mg/kg/day). N = 7 per group. Two-way repeated-measures ANOVA with post hoc Sidak’s test. P values < 0.05 from post hoc test are displayed on graph. Endothelin receptor (ET), high salt (HS), and normal salt (NS)Back to article page