Table 2 Single nucleotide polymorphism analysis of 30 loci in 6 genes in chronic HBV-infected patients and healthy controls

AKR1C2

rs2801904

chr10:5041692

C > A

Intron

0.757

0.750

0.758

rs12414884

chr10:5021206

T > G

Intron

0.189

0.136

0.200

AKR1C3

rs2096421

chr10:5055213

G > A

Intron

0.750

0.735

0.449

rs2398203

chr10:5134591

C > T

Intron

0.189

0.184

0.777

rs2186174

chr10:5134535

A > C

Intron

0.189

0.188

0.955

rs2211623

chr10:5062949

G > C

Intron

0

0

–

rs2154306

chr10:5101710

T > C

Intron

0

0

–

rs4559587

chr10:5100663

C > A

Intron

0

0

–

rs12529

chr10:5094459

C > G

Missense

0

0

–

rs3763676

chr10:5094307

A > G

Intron

0

0

–

HSD17B6

rs4237805

chr12:56855861

G > A

Intron

0.156

0.140

0.350

rs898611

chr12:56769532

C > A

Intron

0.802

0.799

0.868

SRD5A1

rs3797177

chr5:6666971

T > A

Intron

0.216

0.211

0.747

rs248800

chr5:6660287

C > A

Intron

0.223

0.207

0.361

rs1691053

chr5:6677052

T > C

Intron

0.220

0.027

0.417

rs248799

chr5:6694579

G > A

Intron

0

0

–

rs6872996

chr5:6661853

C > T

Intron

0

0

–

SRD5A2

rs2208532

chr2:31563919

G > A

Intron

0.405

0.384

0.320

rs12470143

chr2:31538488

C > T

Intron

0.198

0.286

0.813

rs523349

chr2:31580636

G > C

Missense

0.422

0.418

0.893

rs4952197

chr2:31542061

A > G

Intron

0.564

0.544

0.374

rs7594951

chr2:31566723

C > T

Intron

0.103

0.080

0.066

rs612224

chr2:35186801

C > A

Intron

0.051

0.049

0.452

ESR1

rs6909023

chr6:151832562

G > A

Intron

0.137

0.096

0.974

rs6920483

chr6:151810186

G > A

Intron

0.117

0.114

0.890

rs2077647

chr6:151807942

T > C

Exonic

0.367

0.257

0.493

rs2234693

chr6:151842200

T > C

Intron

0.385

0.368

0.438

rs1062577

chr6:152102770

T > A

UTR3

0.310

0.306

0.848

rs7753153

chr6:151826963

G > A

Intron

0.243

0.238

0.836

rs9340799

chr6:151842246

A > G

Intron

0.204

0.198

0.783