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Table 2 Profile of phosphatidylcholine (PC) and phosphatidylethanolamine (PE) containing DHA and ARA in umbilical cord vein from obese (n = 16) compared to normal BMI women (n = 16) regarding the fetal sex

From: Fetal sex differences in placental LCPUFA ether and plasmalogen phosphatidylethanolamine and phosphatidylcholine contents in pregnancies complicated by obesity

 

Umbilical cord vein

Female

Male

Relative level

Ctr (n = 9)

Ob (n = 11)

q value (FDR)

Ctr (n = 7)

Ob (n = 5)

q value (FDR)

PC-DHA

 PC 14:0_22:6

0.02 ± 0.01

0.01 ± 0.008

> 0.999

0.01 ± 0.007

0.007 ± 0.005

0.258

 PC 16:0_22:6

2.79 ± 1.10

2.14 ± 0.76

0.724

3.25 ± 0.67

1.86 ± 0.54

0.046

 PC O-16:0_22:6

0.19 ± 0.08

0.12 ± 0.06

0.675

0.16 ± 0.04

0.17 ± 0.21

0.242

 PC P-16:0_22:6

0.08 ± 0.03

0.04 ± 0.02

0.673

0.09 ± 0.03

0.04 ± 0.03

0.057

 PC 18:0_22:6

1.87 ± 0.88

1.35 ± 0.50

0.675

1.97 ± 0.23

0.97 ± 0.32

0.041

 PC 18:1_22:6

0.14 ± 0.05

0.11 ± 0.03

0.675

0.14 ± 0.02

0.10 ± 0.02

0.057

 PC O-18:0_22:6

0.17 ± 0.11

0.13 ± 0.05

0.813

0.17 ± 0.06

0.12 ± 0.09

0.363

 PC O-18:1_22:6

0.14 ± 0.09

0.09 ± 0.04

0.675

0.12 ± 0.07

0.09 ± 0.09

0.475

 LPC 22:6

0.35 ± 0.10

0.30 ± 0.10

0.813

0.39 ± 0.04

0.19 ± 0.05

0.041

PC-ARA

 PC 14:0_20:4

0.009 ± 0.002

0.01 ± 0.003

0.813

0.01 ± 0.005

0.01 ± 0.005

0.914

 PC 16:0_20:4

9.47 ± 6.90

10.7 ± 2.50

0.813

12.02 ± 3.97

7.03 ± 5.10

0.242

 PC 16:1_20:4

0.15 ± 0.17

0.04 ± 0.01

0.831

0.15 ± 0.15

0.06 ± 0.08

0.305

 PC O-16:0_20:4

0.89 ± 0.59

1.25 ± 0.39

0.675

1.51 ± 0.73

0.77 ± 0.45

0.216

 PC P-16:0_20:4

0.58 ± 0.51

0.67 ± 0.29

0.813

0.95 ± 0.49

0.39 ± 0.24

0.082

 PC 18:0_20:4

9.20 ± 6.14

10.3 ± 1.97

0.813

12.4 ± 2.64

6.19 ± 4.29

0.057

 PC 18:1_20:4

0.70 ± 0.55

0.82 ± 0.23

0.813

0.96 ± 0.30

0.67 ± 0.22

0.482

 PC 18:2_20:4

0.07 ± 0.03

0.07 ± 0.02

0.813

0.10 ± 0.03

0.05 ± 0.02

0.113

 PC O-18:0_20:4

1.41 ± 1.19

1.29 ± 0.57

0.813

1.47 ± 0.92

1.25 ± 1.30

0.743

 PC O-18:1_20:4

1.32 ± 0.74

1.43 ± 0.61

0.813

1.66 ± 0.89

0.88 ± 0.31

0.299

 PC 20:1_20:4

0.07 ± 0.03

0.08 ± 0.02

0.675

0.08 ± 0.03

0.07 ± 0.01

0.951

 PC 20:2_20:4

0.04 ± 0.02

0.05 ± 0.02

0.813

0.04 ± 0.02

0.05 ± 0.01

0.840

 PC 20:3_20:4

0.05 ± 0.01

0.05 ± 0.01

> 0.999

0.04 ± 0.01

0.04 ± 0.02

0.943

 PC 20:4_20:4

0.04 ± 0.02

0.04 ± 0.01

0.813

0.04 ± 0.01

0.02 ± 0.007

0.055

 LPC 20:4

9.36 ± 3.51

8.36 ± 2.36

0.813

8.26 ± 1.37

5.97 ± 1.36

0.082

LPC

 LPC 16:0

53.8 ± 25.6

66.9 ± 17.7

0.675

81.4 ± 47.7

51.6 ± 9.2

0.639

 LPC 16:1

2.87 ± 1.50

3.51 ± 0.93

0.724

2.49 ± 1.0

2.77 ± 0.45

0.920

 LPC 18:0

9.30 ± 5.94

6.41 ± 1.53

0.675

6.65 ± 1.55

5.25 ± 1.78

0.242

 LPC 18:1

15.1 ± 5.12

16.5 ± 3.98

0.813

13.7 ± 4.24

10.8 ± 2.19

0.242

 LPC 18:2

19.99 ± 8.9

23.14 ± 7.39

0.813

25.8 ± 13.2

13.5 ± 4.22

0.113

 LPC 18:3

0.33 ± 0.20

0.31 ± 0.12

> 0.999

0.25 ± 0.03

0.20 ± 0.05

0.159

 LPC 20:3

4.16 ± 1.02

4.62 ± 1.55

0.813

4.37 ± 0.96

2.68 ± 0.81

0.055

 LPC 20:5

0.30 ± 0.14

0.29 ± 0.14

0.934

0.33 ± 0.10

0.13 ± 0.05

0.055

 LPC 22:4

0.20 ± 0.13

0.11 ± 0.03

0.813

0.17 ± 0.06

0.09 ± 0.03

0.057

PE-DHA

 PE 16:1_22:6

0.06 ± 0.03

0.05 ± 0.02

> 0.999

0.06 ± 0.01

0.04 ± 0.01

0.074

 PE 16:0_22:6

0.85 ± 0.34

0.95 ± 0.29

0.804

1.26 ± 0.37

0.74 ± 0.33

0.074

 PE O-16:0_22:6

0.43 ± 0.21

0.30 ± 0.07

0.456

0.51 ± 0.37

0.30 ± 0.08

0.545

 PE P-16:0_22:6

0.81 ± 0.42

0.52 ± 0.23

0.329

0.98 ± 0.59

0.47 ± 0.15

0.074

 PE 18:0_22:6

0.52 ± 0.35

0.45 ± 0.21

> 0.999

0.66 ± 0.29

0.35 ± 0.12

0.082

 PE O-18:0_22:6

0.07 ± 0.03

0.07 ± 0.02

> 0.999

0.09 ± 0.02

0.04 ± 0.008

0.024

 PE P-18:0_22:6

0.24 ± 0.14

0.15 ± 0.06

0.329

0.34 ± 0.24

0.13 ± 0.03

0.048

 PE 18:1_22:6

0.07 ± 0.01

0.08 ± 0.04

> 0.999

0.11 ± 0.03

0.06 ± 0.02

0.048

 LPE 22:6

0.12 ± 0.05

0.12 ± 0.05

> 0.999

0.14 ± 0.07

0.11 ± 0.03

0.906

PE-ARA

 PE 16:1_20:4

0.14 ± 0.10

0.08 ± 0.03

0.329

0.12 ± 0.06

0.06 ± 0.02

0.232

 PE 16:0_20:4

5.29 ± 2.03

6.97 ± 1.84

0.329

6.02 ± 1.45

6.22 ± 2.02

0.805

 PE O-16:0_20:4

0.68 ± 0.28

0.68 ± 0.28

> 0.999

0.76 ± 0.23

0.48 ± 0.16

0.082

 PE P-16:0_20:4

2.40 ± 1.18

2.12 ± 0.86

> 0.999

2.75 ± 1.08

1.21 ± 0.46

0.049

 PE 18:0_20:4

4.19 ± 1.46

4.76 ± 1.06

0.771

5.17 ± 1.67

3.82 ± 1.80

0.294

 PE O-18:0_20:4

0.56 ± 0.33

0.45 ± 0.18

> 0.999

0.64 ± 0.16

0.35 ± 0.17

0.082

 PE P-18:0_20:4

1.83 ± 1.24

1.37 ± 0.51

> 0.999

2.19 ± 0.75

0.90 ± 0.50

0.048

 PE 18:1_20:4

0.63 ± 0.22

0.74 ± 0.25

> 0.999

0.64 ± 0.19

0.64 ± 0.19

0.957

 PE 18:2_20:4

0.04 ± 0.01

nd

 

0.08 ± 0.07

0.06 ± 0.007

0.945

 LPE 20:4

1.24 ± 0.19

1.86 ± 0.57

0.329

1.26 ± 0.29

1.39 ± 0.91

0.892

  1. 20:4 = ARA, 22:6 = DHA, PC = phosphatidylcholine, PE = phosphatidylethanolamine, LPC = lysophosphatidylcholine, LPE = lysophosphatidylethanolamine. In grey all “O” = ether, “P” = plasmalogen species, nd = not detected. Values are the mean ± SD. In bold, p value < 0.05 after FDR calculation
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Biology of Sex Differences

ISSN: 2042-6410

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