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Fig. 3 | Biology of Sex Differences

Fig. 3

From: Serum metabolomics profiling by proton nuclear magnetic resonance spectrometry of the response to single oral macronutrient challenges in women with polycystic ovary syndrome (PCOS) compared with male and female controls

Fig. 3Fig. 3

Proton nuclear magnetic resonance metabolomics profiling of amino acids, including aromatic and branched-chain amino acids and byproducts, and amino acid-derived metabolites, short-chain fatty acids, ketone bodies and carbohydrates, in response to macronutrient challenges as a function of obesity. Data represent the AUCs (arbitrary units) as means ± SEM. Colors cyan and purple correspond to non-obese and obese individuals, respectively. p < 0.05 for the differences between non-obese and obese individuals, regardless of the macronutrient ingested and group of subjects. p < 0.05 for the interaction between obesity and macronutrient load, irrespective of group. §p < 0.05 for the interaction between obesity and group of subjects, regardless of the macronutrient ingested. p < 0.05 for the triple interaction among obesity, group and macronutrient load. §¶These interactions are described in the main text and Table 2

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