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Fig. 6 | Biology of Sex Differences

Fig. 6

From: Sex differences in renal cell carcinoma: a single-cell analysis reveals exhausted CD8+ T-cells highly infiltrated in males

Fig. 6

Androgen receptor inhibitors can enhance immunotherapy efficacy. A Flowchart of animal experiment in this study. B, C The tumor growth curves and tumor weight showing the effect of androgen and ENZ on tumor growth. D, E The expression of cytotoxicity and exhaustion markers of CD8+ T-cells were evaluated in mouse tumors by IHC. F Schematic representation showing the mechanism of androgen and androgen receptor inhibitors in RCC. ENZ: enzalutamide; IHC: immunohistochemistry; RCC: renal cell carcinoma

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Biology of Sex Differences

ISSN: 2042-6410

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