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Fig. 3 | Biology of Sex Differences

Fig. 3

From: Sex differences in pre- and post-synaptic glutamate signaling in the nucleus accumbens core

Fig. 3

Female mice have a larger readily releasable pool of glutamate and lower release probability in the nucleus accumbens core than male mice. Cumulative EPSC obtained following a 100-Hz train demonstrates a larger response in females compared to males (A; n = 6–7/group). Analysis of the size of the readily releasable pool (RRP) reveals that female mice have a larger RRP of glutamate compared to male mice (B; n = 5–7/group). Female mice also exhibit a lower release probability than male mice (C; n = 5–7/group). *p < 0.05 effect of biological sex

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