Fig. 2
From: Sex differences in pre- and post-synaptic glutamate signaling in the nucleus accumbens core
AMPA/NMDA ratio in the nucleus accumbens core is higher in female C57Bl6/J mice compared to male mice. Whole-cell recordings demonstrated no significant effect of sex on sEPSC amplitude (A, B; n = 19–24/group) or frequency (C, D; n = 18–22/group). Female mice have a significantly higher AMPA/NMDA ratio in this region than male mice (E; n = 12–17/group). Representative traces for sEPSC recordings and AMPA and NMDA currents (F). *p < 0.05 effect of biological sex