Fig. 1

Sex and age interact to influence body mass and adiposity in 3xTg-AD mice. A Raw body mass in male and female 3xTg-AD mice at 3, 6, 9, and 12 months of age. n = 6–10/group. B Body mass normalized to same-sex mice at 3 months of age in male and female 3xTg-AD mice n = 6–10/group. C Subcutaneous adiposity, as calculated by percent body mass, in male and female 3xTg-AD mice at 3, 6, 9, and 12 months of age. n = 4–10/group. D Visceral adiposity, as calculated by percent body mass, in male and female 3xTg-AD mice at 3, 6, 9, and 12 months of age. n = 5–10/group. **p < 0.01 vs. opposite sex of same age, ***p < 0.001 vs. opposite sex of same age, ****p < 0.0001 vs. opposite sex of same age, ^ = p < 0.05 vs. same-sex 3 month; ^^ = p < 0.01 vs. same-sex 3 month; ^^^ = p < 0.001 vs. same-sex 3 month; ^^^^ = p < 0.0001 vs. same-sex 3 month. Data are presented as mean ± SEM