Fig. 2

Sex-specific differences in alveolarization were lost in miR30a^−/− mice in the setting of neonatal hyperoxia exposure: Lung morphometry (mean linear intercept; MLI) and radial alveolar count (RAC) were measured in WT and miR-30a^−/− mice. A Representative hematoxylin and eosin-stained sections from male and female WT or miR-30a^−/− mice in the room air and hyperoxia groups at 40 × magnification. Black bars = 50 µm. B Quantitation of Mean linear intercept (MLI) or C: radial alveolar count (RAC) in neonatal WT and miR-30a^−/− mice exposed to room air or hyperoxia (95% FiO₂, PND 1–5) on PND21. Values are mean ± SE. Independent biological replicates in each group are shown (n = 3–10/group). Significant differences between groups are shown by *P < 0.05, **P < 0.01, and ***P < 0.001. Statistical analysis was performed using 3-way ANOVA