Skip to main content

Table 4 Coronary artery calcification (CAC) is significantly associated with mortality in female kidney failure patients, independent of age

From: Coronary artery calcification and aortic valve calcification in patients with kidney failure: a sex-disaggregated study

Mortality

Males (n = 177)

Females (n = 92)

Univariate

Univariate

Odds ratios

95% CI

p-value

Odds ratios

95% CI

p-value

Age

1.10

1.10–1.14

0.001

1.10

1.03–1.18

0.004

SBP, mmHg

0.96

0.93–0.98

0.001

0.97

0.94 -1.00

0.082

DM, yes

2.67

0.96–7.33

0.061

10.35

2.56–41.7

0.001

Smoking, yes

14.10

2.45–80.9

0.003

n/a

n/a

n/a

Albumin, g/L

0.89

0.82–0.97

0.011

0.81

0.69–0.94

0.007

IL-6, pg/mL

1.15

1.01–1.32

0.036

n/a

n/a

n/a

AGE, skin AF

2.67

1.20–5.97

0.017

1.53

0.82–2.84

0.184

GDF-15, ng/mL

1.22

1.04–1.45

0.018

n/a

n/a

n/a

ln(CAC + 1)

1.64

1.24–2.18

0.001

1.66

1.15–2.39

0.007

 

Multivariate†

Multivariate†

 

Odds ratios

95% CI

p-value

Odds ratios

95% CI

p-value

Age

1.01

0.88–1.15

0.906

1.05

0.97–1.13

0.276

SBP, mmHg

1.05

0.98–1.11

0.149

0.97

0.94–1.00

0.067

Albumin, g/L

0.93

0.72–1.21

0.601

0.75

0.60–0.95

0.019

GDF-15, ng/mL

1.35

1.03–1.77

0.032

n/a

n/a

n/a

ln(CAC + 1)

1.21

0.71–2.05

0.486

1.76

1.12–2.78

0.015

  1. Bold p-values signify significance. n/a signifies a lack of appropriate datapoints to perform analysis
  2. Logistic regression was performed using logarithmic coronary artery calcification expressed as ln(CAC + 1)
  3. AF autofluorescence, AGE advanced glycation end-products, CAC coronary artery calcification, DM diabetes mellitus, GDF-15 growth differentiation factor 15, IL-6 interleukin-6, SBP systolic blood pressure
  4. †Multivariate analysis includes all those significant variables presented in the univariate analyses
Back to article page

Biology of Sex Differences

ISSN: 2042-6410

Contact us