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Table 2 Echocardiographic and cardiovascular magnetic resonance data of male and female patients with hypertrophic cardiomyopathy

From: Sex-related differences in the associations between plasma free fatty acid levels and clinical features in patients with hypertrophic cardiomyopathy

Variable

Male (n = 243)

Female (n = 169)

p value

Echocardiography

 Systolic anterior motion, n (%)

215 (88.5%)

156 (92.3%)

0.242

 LVOT obstruction, n (%)

241 (99.2%)

168 (99.4%)

1.000

 Severe mitral regurgitation, n (%)

13 (5.3%)

11 (6.5%)

0.672

 LVOTG at rest (mmHg)

64.3 ± 35.4

79.6 ± 35.9

<0.001

 LVOTG after provocation (mmHg)a

82.1 ± 31.4

66.3 ± 28.7

0.031

Cardiovascular magnetic resonance

 Left atrium diameter (mm)

42.1 ± 8.1

42.8 ± 8.1

0.362

 LV end-diastolic diameter (mm)

46.8 ± 5.0

45.0 ± 5.2

<0.001

 Maximum wall thickness (mm)

25.3 ± 5.5

23.4 ± 4.9

<0.001

 LV ejection fraction (%)

67.8 ± 8.0

69.1 ± 7.6

0.097

 LV end-diastolic volume (mL)

135.0 ± 34.4

114.3 ± 27.1

<0.001

 LV end-systolic volume (mL)

44.7 ± 18.9

36.4 ± 15.4

<0.001

 Stroke volume (mL)

91.1 ± 23.6

78.4 ± 17.6

<0.001

 Cardiac output (L/min)

6.3 ± 1.8

5.3 ± 1.3

<0.001

 LV mass (g)

181.3 ± 73.7

128.6 ± 54.2

<0.001

 LV end-diastolic volume index (mL/m2)

72.5 ± 16.4

70.1 ± 15.2

0.140

 LV end-systolic volume index (mL/m2)

23.7 ± 9.3

22.0 ± 8.7

0.075

 Stroke volume index (mL/m2)

48.9 ± 11.3

48.1 ± 9.9

0.502

 Cardiac index (L/min/m2)

3.4 ± 0.9

3.3 ± 0.8

0.306

 LV mass index (g/m2)

96.8 ± 37.6

78.6 ± 31.5

<0.001

  1. Data are expressed as mean ± SD or number (percentage)
  2. HCM hypertrophic cardiomyopathy, LV left ventricular, LVOTG left ventricular outflow tract gradient
  3. aProvoked LVOTG data were available in 96 patients